Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP12 | P39900 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP14 | P50281 | 3/20 | 0.39 |
| ▸ | MMP16 | P51512 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049173 | 0.88 | CYP11B1 (0.46) | CYP19A1CYP11B1CYP11B2HSD17B10KDM4E | |
| SCHEMBL3736357 | 0.79 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2AKR1B1TDP1 | |
| SCHEMBL28179114 | 0.76 | CYP11B1 (0.56) | CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL13048283 | 0.73 | CYP11B1 (0.47) | CYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL3733246 | 0.70 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2AKR1B1BRD4 | |
| Iodide SCHEMBL31305035 | 0.70 | AKR1B1 (0.73) | CYP19A1AKR1B1MMP2MMP12MMP8 | |
| Methyl Alcohol SCHEMBL28299530 | 0.68 | AKR1B1 (0.70) | CYP19A1AKR1B1MMP2MMP12MMP8 | |
| SCHEMBL30359 | 0.68 | AKR1B1 (0.76) | AKR1B1MMP2MMP12MMP8MMP13 | |
| SCHEMBL29410826 | 0.68 | AKR1B1 (0.76) | AKR1B1MMP2MMP12MMP8MMP13 | |
| SCHEMBL8954196 | 0.68 | CYP11B1 (0.53) | CYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142652-A1 | IMIDAZOBENZAZEPINE COMPOUNDS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM (CNS) DISEASES | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |