SCHEMBL373637

SCHEMBL373637

C[Si](C)(C)CCCOCC(O)CO

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.58
HTT P42858 1/20 0.39
PLA2G2C Q5R387 1/20 0.35
HSD17B10 Q99714 1/20 0.34
LPAR5 Q9H1C0 1/20 0.34
LMNA P02545 3/20 0.33
CYP1A2 P05177 3/20 0.33
AGTR1 P30556 1/20 0.33
KDM4E B2RXH2 2/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13044735 0.86 USP2 (0.56) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL14962633 0.86 USP2 (0.56) USP2HTTPLA2G2CHSD17B10LPAR5
Acrylic Acid SCHEMBL9418342 0.86 USP2 (0.45) USP2HTTPLA2G2CLPAR5LMNA
Methacrylic Acid SCHEMBL9418391 0.86 USP2 (0.45) USP2HTTPLA2G2CLPAR5LMNA
SCHEMBL19342587 0.85 USP2 (0.51) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL9715030 0.85 USP2 (0.55) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL30514021 0.85 USP2 (0.55) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL16588236 0.83 USP2 (0.53) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL14089863 0.83 USP2 (0.53) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL373471 0.82 USP2 (0.51) USP2HTTPLA2G2CHSD17B10LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496616-A 3D printing orthosis composite material, preparation method and application 广东科恒科技有限公司 2023-07-28 CN claimed
EP-0770888-B1 Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production MENICON CO LTD (JP) 2004-08-04 EP claimed
EP-0657751-B1 Soft ocular lens material MENICON CO LTD (JP) 2003-04-23 EP claimed
US-5670594-A POLYDIMETHYLSILOXANE POLYMERS WITH VINYL OR ACRYLATE GROUPS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1997-09-23 US claimed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
EP-3995493-B1 CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE TOKUYAMA CORP (JP) 2024-07-03 EP disclosed
US-20240026145-A1 OPHTHALMIC LENS MENICON CO., LTD. (JP) 2024-01-25 US disclosed
WO-2023209855-A1 ADDITION TYPE POLYMER AND SILICONE HYDROGEL LENS MATERIAL 株式会社メニコン 2023-11-02 WO disclosed
CN-116496616-A 3D printing orthosis composite material, preparation method and application 广东科恒科技有限公司 2023-07-28 CN disclosed
EP-3936091-B1 METHOD FOR ABSORBING OR DISCHARGING WATER IN OPHTHALMIC MEDICAL DEVICE AND OPHTHALMIC MEDICAL DEVICE UNIV TOHOKU (JP) 2023-07-19 EP disclosed
EP-4206797-A1 OPHTHALMIC LENS Menicon Co., Ltd. (JP) 2023-07-05 EP disclosed
EP-2657304-B1 AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS MENICON CO LTD (JP) 2022-12-07 EP disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0578087-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-01-12 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
US-4954586-A COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE MENICON CO., LTD (JP) 1990-09-04 US disclosed
EP-0381005-A2 Ocular lens material Menicon Co., Ltd. (JP) 1990-08-08 EP disclosed
EP-0379146-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1990-07-25 EP disclosed