SCHEMBL13044735

SCHEMBL13044735

C[Si](O)(O)CCCOCC(O)CO

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.56
HTT P42858 1/20 0.38
PLA2G2C Q5R387 1/20 0.37
HSD17B10 Q99714 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
LMNA P02545 2/20 0.33
CYP1A2 P05177 2/20 0.33
AGTR1 P30556 1/20 0.33
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962633 0.89 USP2 (0.56) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL373637 0.86 USP2 (0.58) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL5854880 0.84 USP2 (0.55) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL1106391 0.84 USP2 (0.51) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL9715030 0.83 USP2 (0.55) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL30514021 0.83 USP2 (0.55) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL14089863 0.81 USP2 (0.53) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL16588236 0.81 USP2 (0.53) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL25638703 0.81 USP2 (0.53) USP2HTTPLA2G2CHSD17B10LPAR5
SCHEMBL373857 0.80 USP2 (0.51) USP2HTTPLA2G2CHSD17B10LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100288963-A1 Modified silica particles and dirt repellent polymer compositions comprising them BASF SE (DE) 2010-11-18 US disclosed
US-7740482-B2 Stable cationically crosslinkable/polymerizable dental composition with a high filler content BLUESTAR SILICONES FRANCE (FR) 2010-06-22 US disclosed
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RFC1, RFC2, HNRNPC USP2 4786/4885HTT 1251/4885PLA2G2C 14/4885
US-20100288963-A1 Modified silica particles and dirt repellent polymer compositions comprising them ITCH, DSTN, CD44 USP2 1225/4885HTT 1865/4885PLA2G2C 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.