Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylbenzene SCHEMBL28611706 | 0.85 | MAPT (0.47) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| SCHEMBL249404 | 0.82 | KMT2A (0.55) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Methacrylic Acid SCHEMBL27554889 | 0.80 | MAPK1 (0.65) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Methacrylic Acid SCHEMBL1596758 | 0.80 | ALDH1A1 (0.50) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Ammonia Solution, Strong SCHEMBL11855911 | 0.79 | KMT2A (0.52) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Trifluoromethylbenzene SCHEMBL28603020 | 0.79 | ALDH1A1 (0.58) | KMT2AMAPTALDH1A1MEN1TSHR | |
| Methacrylic Acid SCHEMBL27561274 | 0.79 | MAPK1 (0.63) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Methacrylic Acid SCHEMBL8850862 | 0.79 | CYP2C19 (0.53) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Methacrylic Acid SCHEMBL27584249 | 0.79 | CYP2C19 (0.40) | KMT2AMAPTCYP2C19HIF1AHDAC3 | |
| Methacrylic Acid SCHEMBL27342660 | 0.79 | CYP2C19 (0.40) | KMT2AMAPTCYP2C19HIF1AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247478-A1 | METHOD FOR STABILIZING VERTEBRAL BODY ARCHITECTURE | STRYKER CORPORATION | 2010-09-30 | — | — | US | claimed |
| WO-2010096487-A1 | METHOD FOR STABILIZING VERTEBRAL BODY ARCHITECTURE | ORTHOVITA, INC. (US) | 2010-08-26 | — | — | WO | claimed |
| CN-109568673-A | Novel antibiotic bone cement and preparation method thereof | 上海尚融生物科技有限公司 | 2019-04-05 | — | — | CN | disclosed |
| US-8647614-B2 | Method for stabilizing vertebral body architecture | ORTHOVITA, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-20100247478-A1 | METHOD FOR STABILIZING VERTEBRAL BODY ARCHITECTURE | STRYKER CORPORATION | 2010-09-30 | — | — | US | disclosed |
| WO-2010096487-A1 | METHOD FOR STABILIZING VERTEBRAL BODY ARCHITECTURE | ORTHOVITA, INC. (US) | 2010-08-26 | — | — | WO | disclosed |
| US-20070173949-A1 | Bonding system for orthopedic implants | SHARPS LEWIS S | 2007-07-26 | — | — | US | disclosed |