Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639714 | 0.86 | TSHR (0.60) | TSHRMAPTCYP3A4TDP1HSD17B10 | |
| SCHEMBL28894376 | 0.86 | TSHR (0.60) | TSHRMAPTCYP3A4TDP1HSD17B10 | |
| SCHEMBL12588750 | 0.84 | TSHR (0.54) | TSHRMAPTCYP3A4POLBTDP1 | |
| SCHEMBL4957182 | 0.82 | TSHR (0.52) | TSHRMAPTCYP3A4POLBTDP1 | |
| SCHEMBL27939248 | 0.81 | TSHR (0.50) | TSHRMAPTCYP3A4POLBTDP1 | |
| SCHEMBL11238853 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11238855 | 0.80 | ALDH1A1 (0.54) | TSHRMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10606385 | 0.80 | TSHR (0.54) | TSHRMAPTCYP3A4TDP1ALDH1A1 | |
| SCHEMBL20610672 | 0.79 | TSHR (0.52) | TSHRMAPTCYP3A4POLBTDP1 | |
| SCHEMBL28198887 | 0.79 | TSHR (0.52) | TSHRMAPTCYP3A4POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7831183-B2 | Electrophotograph developing roller and developing apparatus employing the same | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20080069601-A1 | DEVELOPING ROLLER AND DEVELOPING APPARATUS | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2008-03-20 | — | — | US | disclosed |