SCHEMBL3736895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5959967	0.89	SMN1; SMN2 (0.85)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL3052350	0.88	NPC1 (0.62)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL13416895	0.84	NPC1 (0.66)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL15706789	0.84	NR1H4 (0.71)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL2062609	0.84	NR1H4 (0.78)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL3061782	0.84	NR1H4 (0.78)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL12270961	0.83	NPC1 (0.54)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL19244915	0.82	ACHE (0.57)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL27001784	0.82	NPC1 (0.72)	NPC1RAB9AMAPTSMN1; SMN2NFKB1
	SCHEMBL26095552	0.82	NR1H4 (0.70)	NPC1RAB9AMAPTSMN1; SMN2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.