Triethylene Glycol

Triethylene Glycol

SCHEMBL3736941

CCCCOC(CC(=O)O)C(=O)O.OCCOCCOCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
THRB P10828 1/20 0.49
HTT P42858 1/20 0.49
MAPT P10636 1/20 0.49
RARB P10826 2/20 0.38
CYP3A4 P08684 2/20 0.36
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLCO1B3 Q9NPD5 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
GPR84 Q9NQS5 4/20 0.34
PTPRF P10586 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL3746402 1.00 TSHR (0.53) TSHRMEN1KMT2ATHRBHTT
Di(Hydroxyethyl)Ether SCHEMBL3742578 0.98 TSHR (0.55) TSHRMEN1KMT2ATHRBHTT
SCHEMBL3729354 0.91 TSHR (0.44) TSHRMEN1KMT2ATHRBHTT
SCHEMBL3731202 0.91 TSHR (0.44) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL3732513 0.90 TSHR (0.41) TSHRALDH1A1GPR84PTPRFPTPN2
SCHEMBL14252257 0.90 TSHR (0.41) TSHRMEN1KMT2ATHRBHTT
Di(Hydroxyethyl)Ether SCHEMBL3730783 0.89 TSHR (0.44) TSHRMEN1KMT2ATHRBHTT
1,4-Butanediol SCHEMBL3731759 0.89 TSHR (0.39) TSHRMEN1KMT2AALDH1A1LMNA
SCHEMBL11764465 0.88 GPR84 (0.41) TSHRALDH1A1MAPK1GPR84PTPRF
SCHEMBL9774225 0.87 MEN1 (0.42) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed