Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737344 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2CYP2C19CPA1ABCC4 | |
| SCHEMBL6024479 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2CYP2C19CPA1ABCC4 | |
| SCHEMBL7745831 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2 | |
| SCHEMBL7745838 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2 | |
| SCHEMBL7745830 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2 | |
| SCHEMBL471837 | 0.77 | — | — | |
| SCHEMBL29957191 | 0.77 | — | — | |
| SCHEMBL29953144 | 0.77 | — | — | |
| SCHEMBL11736114 | 0.76 | TSHR (0.34) | GRIK1GRIK2CYP2C19CPA1MAPT | |
| SCHEMBL6648608 | 0.75 | ALDH1A1 (0.42) | GRIK1GRIK2CYP2C19CPA1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905511-B1 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA TECH SARL (CH) | 2013-03-27 | — | — | EP | claimed |
| EP-1448298-B1 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | INVISTA TECH SARL (CH) | 2010-09-22 | — | — | EP | claimed |
| EP-1586598-B1 | Process for preparation of polymeric, phosphorus-containing compositions | INVISTA TECH SARL (CH) | 2009-09-09 | — | — | EP | claimed |
| EP-1571172-B1 | Polymeric, phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA TECH SARL (CH) | 2008-10-22 | — | — | EP | claimed |
| EP-1534657-B1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECH SARL (CH) | 2008-10-08 | — | — | EP | claimed |
| US-7388121-B2 | Process to separate butadiene dimers | DSM IP ASSETS B.V. (NL) | 2008-06-17 | — | — | US | claimed |
| EP-1448668-B1 | POLYMERIC, PHOSPHOROUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, ISOMERIZATION AND HYDROFORMYLATION REACTIONS | DU PONT (US) | 2006-08-09 | — | — | EP | claimed |
| US-20050109605-A1 | Process to separate butadiene dimers from alkyl pentenoates | DSM IP ASSETS B.V. (NL) | 2005-05-26 | — | — | US | claimed |
| EP-1001928-B1 | IMPROVED HYDROCYANATION PROCESS | INVISTA TECH SARL (US) | 2005-04-06 | — | — | EP | claimed |
| EP-1456167-A1 | PROCESS TO SEPARATE BUTADIENE DIMERS FROM ALKYL PENTENOATES | DSM IP Assets B.V. (NL) | 2004-09-15 | — | — | EP | claimed |
| US-5847191-A | Process for the hydrocyanation of monoolefins using bidentate phosphite ligands and zero-valent nickel | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-12-08 | — | — | US | claimed |
| EP-0730574-B1 | PROCESSES AND CATALYST COMPOSITIONS FOR HYDROCYANATION OF MONOOLEFINS | DU PONT (US) | 1998-08-19 | — | — | EP | claimed |
| EP-0715616-B1 | PROCESS FOR THE PREPARATION OF A MIXTURE OF ALKYL PENTENOATES | DSM NV (NL) | 1998-06-03 | — | — | EP | claimed |
| WO-1998019990-A1 | PROCESS FOR THE CONTINUOUS PREPARATION OF AN ALKYL 5-FORMYLVALERATE COMPOUND | DSM N.V. (NL) | 1998-05-14 | — | — | WO | claimed |
| EP-0839794-A1 | Process for the continuous preparation of an alkyl 5-formylvalerate compound | DSM N.V. (NL) | 1998-05-06 | — | — | EP | claimed |
| EP-0815073-A1 | PROCESS FOR HYDROCYANATION IN THE PRESENCE OF ZERO-VALENT NICKEL, A BIDENTATE PHOSPHOROUS COMPOUND AND A LEWIS ACID | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| WO-1996029303-A1 | PROCESS FOR HYDROCYANATION IN THE PRESENCE OF ZERO-VALENT NICKEL, A BIDENTATE PHOSPHOROUS COMPOUND AND A LEWIS ACID | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| US-5523453-A | USING NICKEL COMPLEX CATALYST AND LEWIS ACID PROMOTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-06-04 | — | — | US | claimed |
| EP-0177641-B1 | MANUFACTURE OF BUTANEDICARBOXYLIC ACID ESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | claimed |
| EP-0251728-B1 | CARBOALKOXYLATION OF BUTADIENE TO FORM DIALKYL ADIPATE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-29 | — | — | EP | claimed |