SCHEMBL3737355

SCHEMBL3737355

CC(C)(C[C@H](N)C(=O)O)C(=O)[C@@H](N)CCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.59
GRM8 O00222 2/20 0.59
GRM6 O15303 2/20 0.59
GRM7 Q14831 2/20 0.59
GRM4 Q14833 2/20 0.59
GRIN2D O15399 1/20 0.59
GRIN3B O60391 1/20 0.59
GSR P00390 1/20 0.59
GRIK1 P39086 1/20 0.59
GRM5 P41594 1/20 0.59
GRIA1 P42261 1/20 0.59
GRIA2 P42262 1/20 0.59
GRIA3 P42263 1/20 0.59
SLC1A3 P43003 1/20 0.59
SLC1A2 P43004 1/20 0.59
SLC1A1 P43005 1/20 0.59
GRIA4 P48058 1/20 0.59
GRIN1 Q05586 1/20 0.59
GRIN2A Q12879 1/20 0.59
GRIK2 Q13002 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14312296 0.88 KMT2A (0.60) CYP1A2GRM8GRM6GRM7GRM4
SCHEMBL12420329 0.79 CYP1A2 (0.58) CYP1A2GRM8GRM6GRM7GRM4
SCHEMBL21427150 0.79 CYP1A2 (0.58) CYP1A2GRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL27849133 0.78 GRM8 (0.86) CYP1A2GRM8GRM6GRM7GRM4
SCHEMBL24757397 0.77 CYP1A2 (0.56) CYP1A2GRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL27627916 0.77 GRM8 (0.75) CYP1A2GRM8GRM6GRM7GRM4
Glutamic Acid SCHEMBL27740036 0.77 GRM8 (0.75) CYP1A2GRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL16047348 0.77 GRM8 (0.82) CYP1A2GRM8GRM6GRM7GRM4
Glutamic Acid SCHEMBL1896566 0.77 GRM8 (0.82) CYP1A2GRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL9449715 0.76 GRM8 (0.90) CYP1A2GRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865591-B1 SET OF BIOMARKERS FOR THE DIAGNOSIS OF BRUGADA SYNDROME CARDIOMIX S R L (IT) 2024-04-03 EP claimed
CN-114373510-B Metabolic marker for diagnosing or monitoring lung cancer and screening method and application thereof 武汉迈特维尔医学科技有限公司 2023-12-01 CN claimed
US-20230080158-A1 SET OF BIOMARKERS FOR THE DIAGNOSIS OF BRUGADA SYNDROME CARDIOMIX S.R.L. (IT) 2023-03-16 US claimed
CN-114373510-A Metabolic marker for lung cancer diagnosis or monitoring and screening method and application thereof 武汉迈特维尔生物科技有限公司 2022-04-19 CN claimed
WO-2021161208-A1 SET OF BIOMARKERS FOR THE DIAGNOSIS OF BRUGADA SYNDROME CARDIOMIX S.R.L. (IT) 2021-08-19 WO claimed
EP-3865591-A1 SET OF BIOMARKERS FOR THE DIAGNOSIS OF BRUGADA SYNDROME Cardiomix S.r.l. (IT) 2021-08-18 EP claimed
WO-2020137172-A1 METHOD FOR DIAGNOSING INTERSTITIAL CYSTITIS 公立大学法人奈良県立医科大学 2020-07-02 WO claimed
US-5126245-A REAGENTS FOR ASSAY OF GAMMA-GLUTAMYLTRANSPEPTIDASE UNITIKA LTD. (JP) 1992-06-30 US claimed
EP-0266905-A1 Reagents for assay of gamma-glutamyl-transpeptidase UNITIKA LTD. (JP) 1988-05-11 EP claimed
JP-63094998-A None JP disclosed
EP-3865591-B1 SET OF BIOMARKERS FOR THE DIAGNOSIS OF BRUGADA SYNDROME CARDIOMIX S R L (IT) 2024-04-03 EP disclosed
CN-114373510-B Metabolic marker for diagnosing or monitoring lung cancer and screening method and application thereof 武汉迈特维尔医学科技有限公司 2023-12-01 CN disclosed
US-20230080158-A1 SET OF BIOMARKERS FOR THE DIAGNOSIS OF BRUGADA SYNDROME CARDIOMIX S.R.L. (IT) 2023-03-16 US disclosed
CN-114373510-A Metabolic marker for lung cancer diagnosis or monitoring and screening method and application thereof 武汉迈特维尔生物科技有限公司 2022-04-19 CN disclosed
US-5744452-A IMMUNE SYSTEM DISORDERS, AIDS Wei, Edward T. (US) 1998-04-28 US disclosed
WO-1997019691-A1 GAMMA-L-GLUTAMYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH WEI, EDWARD, T. (US) 1997-06-05 WO disclosed
US-5126245-A REAGENTS FOR ASSAY OF GAMMA-GLUTAMYLTRANSPEPTIDASE UNITIKA LTD. (JP) 1992-06-30 US disclosed
EP-0266905-B1 REAGENTS FOR ASSAY OF GAMMA-GLUTAMYL-TRANSPEPTIDASE UNITIKA LTD. (JP) 1992-04-15 EP disclosed
EP-0266905-A1 Reagents for assay of gamma-glutamyl-transpeptidase UNITIKA LTD. (JP) 1988-05-11 EP disclosed
JP-S6394998-A REAGENT FOR DETERMINING GAMMA-GLUTAMYL TRANSPEPTIDASE UNITIKA LTD 1988-04-26 JP disclosed