Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | GRM8 | O00222 | 1/20 | 0.58 |
| ▸ | GRM6 | O15303 | 1/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GSR | P00390 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.58 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21427150 | 1.00 | CYP1A2 (0.58) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL24757397 | 0.85 | CYP1A2 (0.56) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL16688100 | 0.83 | ALDH1A1 (0.38) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL16017853 | 0.83 | GRIK1 (0.37) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL15745581 | 0.83 | ALOX15 (0.56) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL16017791 | 0.83 | GRIK1 (0.37) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL12420333 | 0.83 | ALDH1A1 (0.38) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL13301965 | 0.83 | ALOX15 (0.56) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL18744452 | 0.82 | GABRP (0.57) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL15334832 | 0.82 | ENPEP (0.42) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206902-B | Method for modifying peptides immobilized on a solid support by means of a traceless reducing cleavable linker molecule | 格瑞罗斯普罗泰恩科技公司 | 2025-02-21 | — | — | CN | claimed |
| US-20220363713-A1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | Belyntic GmbH (DE) | 2022-11-17 | — | — | US | claimed |
| EP-4010352-A1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | Belyntic GmbH (DE) | 2022-06-15 | — | — | EP | claimed |
| CN-114206902-A | Method for modifying a peptide immobilized on a solid support by means of a traceless reductively cleavable linker molecule | 贝兰迪克有限责任公司 | 2022-03-18 | — | — | CN | claimed |
| US-12473328-B2 | Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules | Belyntic GmbH (DE) | 2025-11-18 | — | — | US | disclosed |
| CN-114206902-B | Method for modifying peptides immobilized on a solid support by means of a traceless reducing cleavable linker molecule | 格瑞罗斯普罗泰恩科技公司 | 2025-02-21 | — | — | CN | disclosed |
| EP-4010352-B1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | GYROS PROTEIN TECH AB (SE) | 2023-10-18 | — | — | EP | disclosed |
| US-11541049-B2 | Tetrahydroisoquinoline derivatives, preparation process and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| CN-115380043-A | Exenatide analogue and application thereof | 安医健有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-20220363713-A1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | Belyntic GmbH (DE) | 2022-11-17 | — | — | US | disclosed |
| EP-4010352-A1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | Belyntic GmbH (DE) | 2022-06-15 | — | — | EP | disclosed |
| CN-114206902-A | Method for modifying a peptide immobilized on a solid support by means of a traceless reductively cleavable linker molecule | 贝兰迪克有限责任公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20210052576-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES, PREPARATION PROCESS AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-02-25 | — | — | US | disclosed |
| US-20110172193-A1 | PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | JANSSEN PHARMACEUTICA NV (BE) | 2011-07-14 | — | — | US | disclosed |
| US-20110172193-A1 | PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | JANSSEN PHARMACEUTICA NV (BE) | 2011-07-14 | — | — | US | disclosed |
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220363713-A1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | PTMS, VIP, HM13 | CYP1A2 4484/4885GRM8 1865/4885GRM6 1490/4885 |
| US-20110172193-A1 | PRO-DRUGS OF (E)-7-(3-(2-AMINO-1-FLUOROETHYLIDENE)PIPERIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | ARFGAP1, ABCC1, FPR1 | CYP1A2 474/4885GRM8 2167/4885GRM6 891/4885 |
| US-12473328-B2 | Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules | PTMS, VIP, HM13 | CYP1A2 4292/4885GRM8 2007/4885GRM6 1521/4885 |
| US-11541049-B2 | Tetrahydroisoquinoline derivatives, preparation process and use thereof | CYP3A4, CYP3A43, CYP11B2 | CYP1A2 12/4885GRM8 4079/4885GRM6 4663/4885 |
| US-20210052576-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES, PREPARATION PROCESS AND USE THEREOF | CYP3A4, CYP3A43, CYP11B2 | CYP1A2 12/4885GRM8 4079/4885GRM6 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.