⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947322 | 0.83 | BCL2L1 (0.39) | — | |
| SCHEMBL2491311 | 0.75 | S1PR1 (0.39) | — | |
| SCHEMBL10633131 | 0.74 | LTA4H (0.53) | — | |
| SCHEMBL10104014 | 0.70 | MAOB (0.58) | — | |
| Water SCHEMBL31152424 | 0.69 | POLB (0.43) | — | |
| SCHEMBL15534870 | 0.67 | POLB (0.37) | — | |
| SCHEMBL307778 | 0.67 | — | — | |
| SCHEMBL1648910 | 0.67 | — | — | |
| SCHEMBL3726349 | 0.67 | — | — | |
| SCHEMBL9477975 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619402-A1 | GPR17 MODULATORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024104462-A1 | GPR17 MODULATORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-05-23 | — | — | WO | disclosed |
| US-7829584-B2 | Pyridines and pyridine N-oxides as modulators of thrombin | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-09 | — | — | US | disclosed |
| US-20070225282-A1 | PYRIDINES AND PYRIDINE N-OXIDES AS MODULATORS OF THROMBIN | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | US | disclosed |
| WO-2007109459-A2 | PYRIDINES AND PYRIDINE N-OXIDES AS MODULATORS OF THROMBIN | JANSSEN PHARMACEUTICA, NV (BE) | 2007-09-27 | — | — | WO | disclosed |
| EP-0689534-B1 | AMIDE DERIVATIVES AS 5-HT 1A? LIGANDS | WYETH JOHN & BROTHER LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5629323-A | Amide derivatives as 5-HT1A ligands | JOHN WYETH & BROTHER, LTD. (GB) | 1997-05-13 | — | — | US | disclosed |
| EP-0689534-A1 | AMIDE DERIVATIVES AS 5-HT 1A? LIGANDS | JOHN WYETH & BROTHER LIMITED (GB) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994021611-A1 | AMIDE DERIVATIVES AS 5-HT1A LIGANDS | JOHN WYETH & BROTHER LIMITED (GB) | 1994-09-29 | — | — | WO | disclosed |