SCHEMBL3737730

SCHEMBL3737730

CCCCCCCCCC=CCC=CCC1OC1CC1OC1CCCC(=O)O

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.79
ALOX5 P09917 1/20 0.60
PPARG P37231 6/20 0.59
ALDH1A1 P00352 5/20 0.59
F7 P08709 5/20 0.59
F3 P13726 5/20 0.59
PPARD Q03181 5/20 0.59
PPARA Q07869 5/20 0.59
FABP4 P15090 4/20 0.59
HSD17B10 Q99714 4/20 0.59
FFAR1 O14842 3/20 0.59
LMNA P02545 3/20 0.59
CYP19A1 P11511 3/20 0.59
ALOX15 P16050 3/20 0.59
PTGS1 P23219 3/20 0.59
NR4A2 P43354 3/20 0.59
KDM4E B2RXH2 2/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 2/20 0.59
AKR1C3 P42330 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3735715 0.96 MAPT (0.85) MAPTALOX5PPARGALDH1A1F7
SCHEMBL3735713 0.96 MAPT (0.85) MAPTALOX5PPARGALDH1A1F7
SCHEMBL21214014 0.96 MAPT (0.85) MAPTALOX5PPARGALDH1A1F7
SCHEMBL3741924 0.96 MAPT (0.71) MAPTALOX5PPARGALDH1A1F7
SCHEMBL3752243 0.95 MAPT (0.79) MAPTALOX5PPARGALDH1A1F7
SCHEMBL15335332 0.95 MAPT (0.87) MAPTALOX5PPARGALDH1A1F7
SCHEMBL29809746 0.95 MAPT (0.87) MAPTALOX5PPARGALDH1A1F7
SCHEMBL2508939 0.95 MAPT (0.87) MAPTALOX5PPARGALDH1A1F7
SCHEMBL2508938 0.95 MAPT (0.87) MAPTALOX5PPARGALDH1A1F7
SCHEMBL3746603 0.92 MAPT (0.77) MAPTALOX5PPARGALDH1A1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7834248-B2 comprising 12,13-epoxy-9-octadecenoic acid; generation of preferential coatings, resins, glues, plastics, surfactants and lubricants from renewable plant sources COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-11-16 US disclosed
US-7589253-B2 Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2009-09-15 US disclosed
CN-100482797-C Plant fatty acid epoxygenase genes and uses therefor COMMW SCIENT IND RES ORG (AU) 2009-04-29 CN disclosed
US-20070209092-A1 Plant seed comprising vernolic acid COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, BASF PLANT SCIENCE, GMBH 2007-09-06 US disclosed
EP-0975765-B1 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMW SCIENT IND RES ORG (AU) 2006-10-11 EP disclosed
US-20020166144-A1 Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism BASF PLANT SCIENCE GMBH (DE) 2002-11-07 US disclosed
EP-0975765-A4 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMW SCIENT IND RES ORG (AU) 2002-09-25 EP disclosed
US-6329518-B1 NUCLEIC ACID FROM CREPIS PLANT CODING FOR ENZYME THAT CATALYZES EPOXYGENATION OF CARBON DOUBLE BOND AT DELTA-12 POSITION OF FATTY ACID; EFFICIENT PRODUCTION OF COATINGS, GLUES, PLASTICS, SURFACTANTS AND LUBRICANTS BASF PLANT SCIENCE GMBH (DE) 2001-12-11 US disclosed
CN-1257541-A Plant fatty acid epoxidase and its use COMMW SCIENT IND RES ORG (AU) 2000-06-21 CN disclosed
EP-0975765-A1 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-02-02 EP disclosed
WO-1998046762-A1 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-10-22 WO disclosed