Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | PPARG | P37231 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | F7 | P08709 | 5/20 | 0.64 |
| ▸ | F3 | P13726 | 5/20 | 0.64 |
| ▸ | PPARD | Q03181 | 5/20 | 0.64 |
| ▸ | PPARA | Q07869 | 5/20 | 0.64 |
| ▸ | FABP4 | P15090 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735715 | 1.00 | MAPT (0.85) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL3735713 | 1.00 | MAPT (0.85) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL15335332 | 0.99 | MAPT (0.87) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL29809746 | 0.99 | MAPT (0.87) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL2508939 | 0.99 | MAPT (0.87) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL2508938 | 0.99 | MAPT (0.87) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL3737730 | 0.96 | MAPT (0.79) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL3746603 | 0.96 | MAPT (0.77) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL3754861 | 0.95 | MAPT (0.85) | MAPTPPARGALDH1A1F7F3 | |
| SCHEMBL3754858 | 0.95 | MAPT (0.85) | MAPTPPARGALDH1A1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190231730-A1 | TREATMENT OF A DISEASE MEDIATED BY ARACHIDONIC ACID OR AN EICOSANOID | GADAMIAN ROBERT (US) | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190231730-A1 | TREATMENT OF A DISEASE MEDIATED BY ARACHIDONIC ACID OR AN EICOSANOID | PTGER1, HPGDS, PTGER4 | MAPT 1767/4885PPARG 147/4885ALDH1A1 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.