SCHEMBL3737772

SCHEMBL3737772

FC(F)N1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25359531 0.97 FDPS (0.36)
SCHEMBL3440713 0.96
Hydrochloric Acid SCHEMBL25412817 0.93
SCHEMBL23672272 0.89
Hydrochloric Acid SCHEMBL25415142 0.86
SCHEMBL6398836 0.79 FDPS (0.38)
SCHEMBL1224912 0.74 FDPS (0.33)
SCHEMBL4086239 0.73
SCHEMBL14498520 0.73
SCHEMBL5510379 0.73 FDPS (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12258346-B2 Substituted 6-azabenzimidazole compounds GILEAD SCIENCES, INC. (US) 2025-03-25 US disclosed
US-20240287061-A1 SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS GILEAD SCIENCES, INC. 2024-08-29 US disclosed
US-11897878-B2 Substituted 6-azabenzimidazole compounds GILEAD SCIENCES, INC. (US) 2024-02-13 US disclosed
US-11786524-B2 Pharmaceutical compounds SENTINEL ONCOLOGY LIMITED (GB) 2023-10-17 US disclosed
WO-2023186065-A1 A CYCLIN-DEPENDENT KINASE INHIBITOR Taizhou Eoc Pharma Co., Ltd. (CN) 2023-10-05 WO disclosed
WO-2023171736-A1 MEDICINE CONTAINING VITAMIN D DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT OR SOLVATE THEREOF, USED IN COMBINATION WITH IMMUNOMODULATORY SUBSTANCE 帝人ファーマ株式会社 2023-09-14 WO disclosed
WO-2023151642-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 WO disclosed
US-20220213091-A1 SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS GILEAD SCIENCES, INC. 2022-07-07 US disclosed
WO-2022059684-A1 VITAMIN D DERIVATIVE HAVING CYCLIC AMINE IN SIDE CHAIN 帝人ファーマ株式会社 2022-03-24 WO disclosed
US-11203591-B2 Substituted 6-azabenzimidazole compounds GILEAD SCIENCES, INC. (US) 2021-12-21 US disclosed
WO-2014134341-A1 PERFLUORINATED 5,6-DIHYDRO-4H-1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE AMGEN INC. (US) 2014-09-04 WO disclosed
US-7829741-B2 Process for producing α, α-difluoroamine NATIONAL UNIVERSITY CORPORATION (JP) 2010-11-09 US disclosed
US-20090177012-A1 PROCESS FOR PRODUCING ALPHA, ALPHA-DIFLUOROAMINE NATIONAL UNIVERSITY CORPORATION, HOKKAIDO UNIVERSITY (JP) 2009-07-09 US disclosed
CN-101012174-A Halogenating agents MITSUI CHEMICALS INC (JP) 2007-08-08 CN disclosed
EP-1813596-A1 PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE National University Corporation Hokkaido University (JP) 2007-08-01 EP disclosed
WO-2007067362-A1 IN SITU FLUORIDE ION-GENERATING COMPOSITIONS AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-06-14 WO disclosed
US-20070129273-A1 In situ fluoride ion-generating compositions and uses thereof 3M INNOVATIVE PROPERTIES COMPANY 2007-06-07 US disclosed
CN-1202086-C Halogenating agents MITSUI CHEMICAL CO LTD (JP) 2005-05-18 CN disclosed
CN-1483727-A Halogenating agents ������ѧ��ʽ���� 2004-03-24 CN disclosed
CN-1218803-A Halogenating agents MITSUI CHEMICAL CO LTD (JP) 1999-06-09 CN disclosed