⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258289 | 1.00 | — | — | |
| SCHEMBL9025464 | 1.00 | MGLL (0.35) | — | |
| SCHEMBL465305 | 1.00 | — | — | |
| SCHEMBL5465 | 0.95 | — | — | |
| SCHEMBL5126 | 0.80 | — | — | |
| SCHEMBL1802092 | 0.68 | — | — | |
| SCHEMBL3439854 | 0.64 | — | — | |
| SCHEMBL18138135 | 0.64 | — | — | |
| SCHEMBL8225474 | 0.64 | — | — | |
| SCHEMBL2457046 | 0.60 | MGLL (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10753 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147659-A1 | COMPOSITION AND SOFT CAPSULE FORMULATION COMPRISING NAPHTHOQUINONE-BASED COMPOUND | (주)나디안바이오 | 2024-07-11 | — | — | WO | claimed |
| WO-2024120454-A1 | BIS-PHOSPHATIDYL AMINE COMPOUNDS CONTAINING MULTIPLE TERTIARY AMINO STRUCTURES, AND COMPOSITION AND USE THEREOF | 北京大学 | 2024-06-13 | — | — | WO | claimed |
| CN-118146262-A | Bi-phosphatidyl amide compound containing multiple tertiary amino structures, composition and application thereof | 北京大学 | 2024-06-07 | — | — | CN | claimed |
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| EP-4370206-A1 | ESTERS OF 7-COOH CBD DERIVATIVES AND THEIR USE AS PREVENTION, PROPHYLAXIS OF PROGRESSION, AND/OR TREATMENT OF NEUROGENERATIVE DISEASES | Receptorpharma Inc S-Corp (US) | 2024-05-22 | — | — | EP | claimed |
| EP-4370522-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | Nikang Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117980310-A | Alkylene derivatives as KRAS inhibitors | 尼坎治疗公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2024078555-A1 | PYRIMIDOPYRIDINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-04-18 | — | — | WO | claimed |
| CN-117886833-A | Pyrimidopyridine compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| EP-0024510-B1 | PHENOXYPROPYL AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1983-10-19 | — | — | EP | claimed |
| EP-0089765-A2 | Pyridine derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-09-28 | — | — | EP | claimed |
| EP-0081955-A2 | Benzo-fused heterocyclic compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-06-22 | — | — | EP | claimed |
| EP-0062834-A1 | Thiocarbamic-acid esters, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-20 | — | — | EP | claimed |
| EP-0042593-A1 | Aryloxy-propanol amines, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | claimed |
| US-4137315-A | ANTIMICROBIAL, ANTIFUNGAL, ANTISEPTICS | RHONE-POULENC INDUSTRIES (FR) | 1979-01-30 | — | — | US | claimed |
| US-4097592-A | O- 1-substituted-6-pyridazinon(3)yl!-thionoalkanephosphonic acid esters for combating insects and acarids | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | claimed |
| US-3994891-A | VASODILATORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1976-11-30 | — | — | US | claimed |
| US-3993648-A | Tetrahydro-2-(nitromethylene)-2H-1,3-thiazines | SHELL OIL COMPANY (US) | 1976-11-23 | — | — | US | claimed |
| US-3939161-A | ANTIINFLAMMATORY, ANTISECRETORY | ABBOTT LABORATORIES (US) | 1976-02-17 | — | — | US | claimed |