SCHEMBL3738280

SCHEMBL3738280

Cc1cc(C)c(N(Cc2c(-c3cccc4c3Cc3ccccc3-4)ccc3ccccc23)[Ti](Cl)Cl)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32
HTR7 P34969 3/20 0.31
HTR1A P08908 2/20 0.31
ACHE P22303 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6676385 0.84 PNMT (0.35) PNMTHTR7HTR1AACHE
Hydrochloric Acid SCHEMBL3738279 0.83 PNMT (0.33) PNMTHTR7HTR1ACYP1A2CYP2A6
SCHEMBL3745212 0.82 PNMT (0.43) PNMTALDH1A1TSHRATMNPSR1
SCHEMBL3750229 0.79 PNMT (0.36) PNMTHTR7HTR1AACHECYP1A2
SCHEMBL3262857 0.77 CYP1A2 (0.33) CYP1A2CYP2A6ALDH1A1
SCHEMBL3675927 0.77 MEN1 (0.38) PNMTHTR7HTR1AACHECYP1A2
SCHEMBL3680491 0.76 NPC1 (0.36) PNMTHTR7HTR1AALDH1A1TSHR
Hydrochloric Acid SCHEMBL3750227 0.72 PNMT (0.35) PNMTHTR7HTR1AACHECYP1A2
SCHEMBL3742379 0.71 PNMT (0.37) PNMTHTR7HTR1AACHECYP1A2
SCHEMBL3672084 0.71 PNMT (0.43) PNMTHTR7HTR1AACHECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 PNMT 1804/4885HTR7 3440/4885HTR1A 1017/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 PNMT 1804/4885HTR7 3440/4885HTR1A 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.