Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354230 | 1.00 | XDH (0.38) | XDHKDM4ECSNK2A1DPP4DYRK1A | |
| Hydrochloric Acid SCHEMBL4763242 | 0.98 | XDH (0.37) | XDHKDM4ECSNK2A1DPP4DYRK1A | |
| SCHEMBL11456966 | 0.98 | XDH (0.37) | XDHKDM4ECSNK2A1DPP4DYRK1A | |
| Purine SCHEMBL10869620 | 0.82 | RPS6KA5 (0.33) | — | |
| Tetrabuthylammonium SCHEMBL3029322 | 0.81 | SLC22A1 (0.34) | XDHKMT2A | |
| Benzoic Acid SCHEMBL22345211 | 0.81 | NAPRT (0.40) | KDM4ECDK5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL16147017 | 0.79 | XDH (0.36) | XDHKDM4ECSNK2A1DYRK1AAURKA | |
| SCHEMBL2997391 | 0.79 | CSNK2A1 (0.36) | KDM4ECSNK2A1DPP4DYRK1AAURKA | |
| 6-Chloroguanine SCHEMBL6711 | 0.79 | DPP4 (0.52) | CSNK2A1DPP4DYRK1AAURKADAPK3 | |
| SCHEMBL2352412 | 0.79 | CSNK2A1 (0.41) | KDM4ECSNK2A1DPP4DYRK1AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3354 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129105-A1 | COMPOSITION AND METHOD FOR DETECTION OF BIOMOLECULES VIA AROMATIC LABELING USING HETEROCYCLIC COMPOUNDS | Life Technologies Corporation (US) | 2025-06-19 | — | — | WO | claimed |
| EP-4560315-A2 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | F. Hoffmann-La Roche AG (CH) | 2025-05-28 | — | — | EP | claimed |
| EP-3980554-B1 | HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES | HOFFMANN LA ROCHE (CH) | 2025-03-26 | — | — | EP | claimed |
| CN-117987495-A | Synthesis method of 2, 6-dichloropurine nucleoside | 上海瑞合达医药科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117986256-A | Aggregation-induced emission type photosensitizer based on purine skeleton and preparation method and application thereof | 四川大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117467726-B | Preparation method of purine nucleoside | 天津凯莱英生物科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117467726-A | Preparation method of purine nucleoside | 天津凯莱英生物科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| WO-2023177312-A2 | INHIBITOR OF CELLULAR PURINE NUCLEOTIDE SALVAGE PATHWAY ENZYME FOR USE IN THE TREATMENT AND/OR PREVENTION OF HELICOBACTER PYLORI INFECTION AND/OR DISEASE ASSOCIATED WITH SUCH INFECTION AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | UNIWERSYTET WARSZAWSKI (PL) | 2023-09-21 | — | — | WO | claimed |
| CN-116287067-A | Preparation method of 2, 6-dichloropurine nucleoside and enzyme | 上海合全药物研发有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-114349754-B | Synthesis method of 2, 6-dichloropurine | 杭州瑞思新材料有限公司 | 2023-05-12 | — | — | CN | claimed |
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | claimed |
| EP-0152965-B1 | PROCESS FOR PREPARING 2,6-SUBSTITUTED-9-(1,3-DIHYDROXY-2-PROPOXY-MENTHYL)-PURINES AND CERTAIN DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1990-10-24 | — | — | EP | claimed |
| EP-0391411-A2 | 3'-Substituted methyl nucleosides as antiviral agents | Bristol-Myers Squibb Company (US) | 1990-10-10 | — | — | EP | claimed |
| EP-0173059-B1 | METHOD FOR THE PRODUCTION OF 2'-DEOXYADENOSINE COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 1989-11-29 | — | — | EP | claimed |
| US-4801710-A | Regioselective synthesis of 9-substituted purine acyclonucleoside derivatives | MERCK & CO., INC. (US) | 1989-01-31 | — | — | US | claimed |
| US-4760137-A | Method for the production of 2'-deoxyadenosine compounds | BRIGHAM YOUNG UNIVERSITY (US) | 1988-07-26 | — | — | US | claimed |
| US-4621140-A | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-11-04 | — | — | US | claimed |
| EP-0184473-A1 | Regioselective synthesis of 9-substituted purine acyclonucleoside derivatives | MERCK & CO. INC. (US) | 1986-06-11 | — | — | EP | claimed |
| EP-0173059-A2 | Method for the production of 2'-deoxyadenosine compounds | BRIGHAM YOUNG UNIVERSITY (US) | 1986-03-05 | — | — | EP | claimed |
| EP-0152965-A2 | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxy-menthyl)-purines and certain derivatives | SYNTEX (U.S.A.) INC. (US) | 1985-08-28 | — | — | EP | claimed |