Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68353 | 0.97 | — | — | |
| SCHEMBL11028940 | 0.97 | MAOA (0.40) | — | |
| Fluoride SCHEMBL22283858 | 0.94 | — | — | |
| Iodide SCHEMBL3709535 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL28277460 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL2171904 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL28742553 | 0.94 | MAOA (0.39) | — | |
| Ethylene SCHEMBL28836803 | 0.91 | MAOA (0.37) | — | |
| Acetonitrile SCHEMBL7030137 | 0.87 | GAA (0.34) | — | |
| SCHEMBL4624283 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250041843-A1 | PIPERIDINIUM-CONTAINING POLYMERS | VERSOGEN, INC. | 2025-02-06 | — | — | US | claimed |
| WO-2024137720-A2 | PIPERIDINIUM-CONTAINING ANION EXCHANGE POLYMERS | VERSOGEN, INC. (US) | 2024-06-27 | — | — | WO | claimed |
| CN-111954571-B | Poly (arylpiperidinium) polymers including those having stable cationic pendant groups for use as anion exchange membranes and ionomers | 特拉华大学 | 2023-08-04 | — | — | CN | claimed |
| US-11512156-B2 | Poly(aryl piperidinium) polymers including those with stable cationic pendant groups for use as anion exchange membranes and ionomers | UNIVERSITY OF DELAWARE (US) | 2022-11-29 | — | — | US | claimed |
| US-20210009726-A1 | POLY(ARYL PIPERIDINIUM) POLYMERS INCLUDING THOSE WITH STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES AND IONOMERS | UNIVERSITY OF DELAWARE | 2021-01-14 | — | — | US | claimed |
| CN-111954571-A | Poly (arylpiperidinium) polymers including those having stable cationic side groups for use as anion exchange membranes and ionomers | 特拉华大学 | 2020-11-17 | — | — | CN | claimed |
| EP-3687671-A2 | POLY(ARYL PIPERIDINIUM) POLYMERS INCLUDING THOSE WITH STABLE CATIONIC PENDANT GROUPS FOR USE AS ANION EXCHANGE MEMBRANES AND IONOMERS | Yan, Yushan (US) | 2020-08-05 | — | — | EP | claimed |
| EP-1049674-B1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-02-28 | — | — | EP | claimed |
| US-6437136-B2 | Process for the preparation of (−)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)piperidine | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-20 | — | — | US | claimed |
| US-20010051728-A1 | Process for the preparation of (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)piperidine | AVENTIS PHARMA DEUTSCHLAND GMBH. | 2001-12-13 | — | — | US | claimed |
| US-6225473-B1 | REACTING 1-METHYLPIPERIDIN-4-ONE HYDROBROMIDE WITH BROMINE; REACTING WITH 1,3,5-TRIMETHOXYBENZENE; REACTING SOLID WITH WATER TO PRODUCE 3(R,S)-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXY-PHENYL)-1,2,3,6-TE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-05-01 | — | — | US | claimed |
| EP-1049674-A1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | Aventis Pharma Deutschland GmbH (DE) | 2000-11-08 | — | — | EP | claimed |
| WO-1999037615-A1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-29 | — | — | WO | claimed |
| US-20250041843-A1 | PIPERIDINIUM-CONTAINING POLYMERS | VERSOGEN, INC. | 2025-02-06 | — | — | US | disclosed |
| CN-118546339-A | Polyarylpiperidine electrolyte material containing fluorocarbon main chain and application thereof | 广东鸣洋科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20240246070-A1 | PIPERIDINIUM-CONTAINING ANION EXCHANGE POLYMERS | VERSOGEN, INC. | 2024-07-25 | — | — | US | disclosed |
| US-20010051728-A1 | Process for the preparation of (-)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)piperidine | AVENTIS PHARMA DEUTSCHLAND GMBH. | 2001-12-13 | — | — | US | disclosed |
| US-6225473-B1 | REACTING 1-METHYLPIPERIDIN-4-ONE HYDROBROMIDE WITH BROMINE; REACTING WITH 1,3,5-TRIMETHOXYBENZENE; REACTING SOLID WITH WATER TO PRODUCE 3(R,S)-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXY-PHENYL)-1,2,3,6-TE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-05-01 | — | — | US | disclosed |
| EP-1049674-A1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | Aventis Pharma Deutschland GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037615-A1 | METHOD FOR PRODUCING (-)CIS-3-HYDROXY-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PIPERIDINE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-29 | — | — | WO | disclosed |