Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3740258

C#C[C@H]1CC[C@@H](C#N)N1C(=O)[C@@H](N)C1CC2CCC(C1)N2C(=O)c1ccc(C(F)(F)F)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 13/20 0.51
DPP8 Q6V1X1 3/20 0.51
ELOVL6 Q9H5J4 1/20 0.48
FAP Q12884 2/20 0.41
DPP9 Q86TI2 2/20 0.41
DPP7 Q9UHL4 2/20 0.39
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD11B1 P28845 1/20 0.37
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045329 0.96 DPP4 (0.55) DPP4DPP8ELOVL6FAPDPP9
SCHEMBL13078719 0.96 DPP4 (0.55) DPP4DPP8ELOVL6FAPDPP9
Trifluoroacetic Acid SCHEMBL3747927 0.91 DPP4 (0.51) DPP4DPP8ELOVL6DPP7
Trifluoroacetic Acid SCHEMBL3741768 0.86 DPP4 (0.46) DPP4DPP8ELOVL6DPP9
Trifluoroacetic Acid SCHEMBL3738343 0.85 DPP4 (0.58) DPP4
Trifluoroacetic Acid SCHEMBL3741051 0.85 DPP4 (0.46) DPP4DPP8MGLL
SCHEMBL3755839 0.84 DPP4 (0.58) DPP4DPP8GAA
Trifluoroacetic Acid SCHEMBL3744761 0.84 DPP4 (0.57) DPP4DPP8FAPDPP9DPP7
Trifluoroacetic Acid SCHEMBL3742063 0.82 DPP4 (0.51) DPP4ELOVL6
Trifluoroacetic Acid SCHEMBL3738861 0.81 ELOVL6 (0.45) DPP4DPP8ELOVL6FAPDPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338450-B2 Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors LUPIN LIMITED (IN) 2012-12-25 US claimed
US-20100291020-A1 NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS LUPIN LIMITED (IN) 2010-11-18 US claimed
US-8338450-B2 Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors LUPIN LIMITED (IN) 2012-12-25 US disclosed
US-20100291020-A1 NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS LUPIN LIMITED (IN) 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291020-A1 NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS DPP4, DPP7, DPP3 DPP4 1/4885DPP8 5/4885ELOVL6 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.