Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 15/20 | 0.51 |
| ▸ | SCN1A | P35498 | 14/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 14/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715080 | 0.92 | SCN9A (0.56) | SCN9ASCN5ASCN1ASCN8ACYP3A4 | |
| SCHEMBL710121 | 0.92 | SCN9A (0.57) | SCN9ASCN5ASCN1ASCN8ACYP3A4 | |
| SCHEMBL713543 | 0.85 | SCN9A (0.60) | SCN9ASCN5ASCN1ASCN8ACYP3A4 | |
| SCHEMBL713308 | 0.83 | SCN9A (0.69) | SCN9ASCN5ASCN1ASCN8A | |
| SCHEMBL711707 | 0.80 | SCN9A (0.51) | SCN9ASCN5ASCN1ASCN8A | |
| SCHEMBL714026 | 0.79 | SCN9A (0.53) | SCN9ASCN5ASCN1ASCN8A | |
| SCHEMBL714858 | 0.79 | SCN9A (0.61) | SCN9ASCN5ASCN1ASCN8ASCN1B | |
| SCHEMBL714098 | 0.79 | SCN9A (0.52) | SCN9ASCN5ASCN1ASCN8ACYP3A4 | |
| SCHEMBL711742 | 0.78 | SCN9A (0.51) | SCN9ASCN5ASCN1ASCN8A | |
| SCHEMBL710922 | 0.77 | SCN9A (0.55) | SCN9ASCN1ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173743-A2 | SODIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009012242-A2 | SODIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2009-01-22 | — | — | WO | disclosed |