Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SCN8A | Q9UQD0 | 14/20 | 0.54 |
| ▸ | SCN1A | P35498 | 11/20 | 0.54 |
| ▸ | SCN1B | Q07699 | 4/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713308 | 0.91 | SCN9A (0.69) | SCN9ALMNASMN1; SMN2SCN8ASCN1A | |
| SCHEMBL711703 | 0.85 | SCN9A (0.59) | SCN9ALMNASMN1; SMN2SCN5ASCN3A | |
| SCHEMBL710723 | 0.85 | SCN9A (0.61) | SCN9ASCN8ASCN1ASCN5ASCN3A | |
| SCHEMBL710121 | 0.82 | SCN9A (0.57) | SCN9ASCN8ASCN1ASCN5A | |
| SCHEMBL714026 | 0.82 | SCN9A (0.53) | SCN9ALMNASMN1; SMN2SCN8ASCN1A | |
| SCHEMBL711210 | 0.82 | SCN9A (0.57) | SCN9ALMNASMN1; SMN2SCN8ASCN1A | |
| SCHEMBL715212 | 0.82 | SCN9A (0.57) | SCN9ASCN5ASCN3A | |
| SCHEMBL715080 | 0.81 | SCN9A (0.56) | SCN9ASCN8ASCN1ASCN5A | |
| SCHEMBL3173621 | 0.81 | SCN3A (0.60) | SCN9ALMNASMN1; SMN2SCN5ASCN3A | |
| SCHEMBL3740544 | 0.79 | SCN9A (0.55) | SCN9ASCN8ASCN1ASCN1BSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | claimed |
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2173743-A2 | SODIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | ICAGEN (US) | 2009-01-22 | — | — | US | disclosed |
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | ICAGEN (US) | 2009-01-22 | — | — | US | disclosed |
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | ICAGEN (US) | 2009-01-22 | — | — | US | disclosed |
| WO-2009012242-A2 | SODIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009012242-A2 | SODIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | TRPV1, SCN1A, SCN2A | SCN9A 17/4885LMNA 2921/4885SMN1; SMN2 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.