Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.40 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | STK25 | O00506 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | MUSK | O15146 | 1/20 | 0.39 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PAK3 | O75914 | 1/20 | 0.39 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374194 | 0.92 | MET (0.50) | METAXLKDRPLK4STK25 | |
| SCHEMBL373947 | 0.85 | MET (0.42) | METAXLKDRPLK4STK25 | |
| SCHEMBL3418984 | 0.81 | AXL (0.42) | METAXLKDRPLK4STK25 | |
| SCHEMBL374071 | 0.78 | MET (0.55) | METAXLKDRPLK4STK25 | |
| SCHEMBL11914231 | 0.77 | MET (0.57) | METAXLKDRPLK4STK25 | |
| Hydrochloric Acid SCHEMBL377110 | 0.76 | MET (0.39) | METAXLKDRPLK4STK25 | |
| SCHEMBL3421924 | 0.74 | MET (0.54) | METAXLKDRPLK4STK25 | |
| SCHEMBL374249 | 0.73 | AXL (0.42) | METAXLKDRAURKARIPK2 | |
| SCHEMBL411270 | 0.72 | MET (0.63) | METAXLKDRPLK4STK25 | |
| SCHEMBL371886 | 0.72 | MET (0.61) | METAXLKDRPLK4STK25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408300-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd (CN) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010111063-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | XI NING (US) | 2010-09-30 | — | — | WO | disclosed |