SCHEMBL374099

SCHEMBL374099

CC(=O)C(C)(C(C)=O)C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TSHR P16473 3/20 0.39
THPO P40225 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ALDH1A1 P00352 5/20 0.38
GAA P10253 1/20 0.36
CA1 P00915 2/20 0.36
ALOX15 P16050 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CA2 P00918 1/20 0.31
PTGS1 P23219 1/20 0.31
MMP12 P39900 1/20 0.31
CA4 P22748 1/20 0.31
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750452 0.81 TSHR (0.47) LMNATSHRTHPOFFAR3LCK
SCHEMBL3257772 0.76 LMNA (0.46) LMNATSHRTHPOFFAR3LCK
SCHEMBL3229564 0.76
SCHEMBL43148 0.76
SCHEMBL10693856 0.73 TDP1 (0.42) FFAR3ALDH1A1GAATDP1
Bromide SCHEMBL2967312 0.73
SCHEMBL93224 0.73
Hydrochloric Acid SCHEMBL2970862 0.73
Ammonia Solution, Strong SCHEMBL8089310 0.73
SCHEMBL124447 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102341360-A PROCESS FOR CATALYTIC HALOGENATION OF DIOL AKZO NOBEL NV 2012-02-01 CN claimed
EP-2408730-A1 PROCESS FOR THE CATALYTIC HALOGENATION OF A DIOL Akzo Nobel N.V. (NL) 2012-01-25 EP claimed
CN-106604963-B Vinyl chloride resin stabiliser compositions, vinyl chloride resin composition and its formed products containing the stabiliser compositions ADEKA株式会社 2019-11-26 CN disclosed
CN-106957256-A Diacetyl methine acetone of 1 (3 N substituted carbazoles base) 3 aryl 3 and preparation method thereof 陕西科技大学 2017-07-18 CN disclosed
CN-106957256-A Diacetyl methine acetone of 1 (3 N substituted carbazoles base) 3 aryl 3 and preparation method thereof 陕西科技大学 2017-07-18 CN disclosed
CN-106604963-A Stabilizer composition for vinyl chloride resin, vinyl chloride resin composition using said stabilizer composition, and molded article obtained from said resin composition ADEKA株式会社 2017-04-26 CN disclosed
EP-2408730-A1 PROCESS FOR THE CATALYTIC HALOGENATION OF A DIOL Akzo Nobel N.V. (NL) 2012-01-25 EP disclosed
EP-1490412-B1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2011-03-09 EP disclosed
CN-100473667-C Photoinitiator, novel compound and photocurable composition DAINIPPON INK & CHEMICALS (JP) 2009-04-01 CN disclosed
US-7371739-B2 Aryl fructose-1,6-bisphosphatase inhibitors METABASIS THERAPEUTICS, INC. (US) 2008-05-13 US disclosed
US-7166648-B2 Photoinitiator, novel compound, and photocurable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050256218-A1 Photoinitiator, novel compound, and photocurable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-11-17 US disclosed
CN-1642992-A Photoinitiator, photocurable composition of novel compound DAINIPPON INK & CHEMICALS (JP) 2005-07-20 CN disclosed
EP-1490412-A1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-12-29 EP disclosed
WO-2003082929-A1 PHOTOINITIATOR, NOVEL COMPOUND, AND PHOTOCURABLE COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-10-09 WO disclosed
US-4020073-A Process for O-acylating thallus salts of 2-pyridone TAYLOR EDWARD C 1977-04-26 US disclosed
US-3947488-A O-Acylation using organothallium compounds TAYLOR EDWARD C 1976-03-30 US disclosed