Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | FABP2 | P12104 | 2/20 | 0.63 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CNR1 | P21554 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20704080 | 0.92 | PPARA (0.56) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL28397895 | 0.89 | PPARA (0.61) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL11431131 | 0.88 | PPARA (0.62) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL2822423 | 0.85 | NR4A2 (0.56) | PPARAPPARGCYP1A2CYP3A4KMT2A | |
| SCHEMBL28910816 | 0.84 | PPARA (0.53) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL20704120 | 0.83 | PPARA (0.68) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL12573590 | 0.83 | PPARA (0.67) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL12573936 | 0.83 | PPARA (0.86) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| SCHEMBL15674282 | 0.82 | PPARA (0.65) | PPARAPPARGFABP2SLC22A12CYP1A2 | |
| Fenofibric Acid SCHEMBL10966358 | 0.81 | PPARA (0.77) | PPARAPPARGFABP2SLC22A12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115305488-A | High-energy material containing azide-tetrazole and preparation method thereof | 福州大学 | 2022-11-08 | — | — | CN | disclosed |
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2009073138-A2 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | AMPLA PHARMACEUTICALS INC. (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292289-A1 | TREATMENT OF METABOLIC SYNDROME WITH NOVEL AMIDES | GPR119, CPT1A, GLS2 | PPARA 147/4885PPARG 134/4885FABP2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.