⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313031 | 0.92 | — | — | |
| SCHEMBL237795 | 0.85 | TSHR (0.50) | — | |
| SCHEMBL515199 | 0.85 | TSHR (0.43) | — | |
| SCHEMBL688762 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL7945150 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL687820 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL2762078 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL27819302 | 0.82 | — | — | |
| SCHEMBL28016201 | 0.80 | — | — | |
| SCHEMBL7627037 | 0.78 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595973-B1 | A PROCESS FOR THE PRODUCTION OF CARNITINE FROM BETA-LACTONES | LONZA AG (CH) | 2017-07-12 | — | — | EP | disclosed |
| US-9394238-B2 | Process for the production of carnitine from β-lactones | LONZA LTD. (CH) | 2016-07-19 | — | — | US | disclosed |
| CN-103003257-B | For being produced the method for carnitine by β-lactone | LONZA LTD. (CH) | 2016-03-16 | — | — | CN | disclosed |
| US-20150126775-A1 | PROCESS FOR THE PRODUCTION OF CARNITINE FROM BETA-LACTONES | LONZA LTD. (CH) | 2015-05-07 | — | — | US | disclosed |
| CN-103003257-A | A process for the production of carnitine from [beta] -lactones | LONZA AG | 2013-03-27 | — | — | CN | disclosed |
| EP-2468739-A1 | A process for the production of carnitine from B-lactones | Lonza Ltd. (CH) | 2012-06-27 | — | — | EP | disclosed |
| US-20120022288-A1 | PROCESS FOR THE PRODUCTION OF CARNITINE FROM BETA-LACTONES | LONZA LTD. (CH) | 2012-01-26 | — | — | US | disclosed |
| EP-2409972-A1 | A process for the production of carnitine from B-lactones | Lonza Ltd. (CH) | 2012-01-25 | — | — | EP | disclosed |