Sugi Predict

Sugi Predict / Compounds / Thiram

Thiram

Thiram

SCHEMBL3741643

CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.[S-2].[S-2].[S-2].[S-2].[S-2].[S-2]

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.93
▸ MGLL Q99685 8/20 0.93
▸ ALDH2 P05091 5/20 0.93
▸ LMNA P02545 3/20 0.93
▸ HTT P42858 3/20 0.93
▸ TP53 P04637 3/20 0.93
▸ HPGD P15428 3/20 0.93
▸ ALOX15 P16050 3/20 0.93
▸ ALOX12 P18054 3/20 0.93
▸ HSD17B10 Q99714 3/20 0.93
▸ FAAH O00519 3/20 0.93
▸ MAPT P10636 3/20 0.93
▸ KMT2A Q03164 3/20 0.93
▸ HSP90AA1 P07900 2/20 0.93
▸ CYP3A4 P08684 2/20 0.93
▸ FBP1 P09467 2/20 0.93
▸ PKM P14618 2/20 0.93
▸ LOX P28300 2/20 0.93
▸ LOXL3 P58215 2/20 0.93
▸ NPSR1 Q6W5P4 2/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiram SCHEMBL223860 1.00 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL1216571 0.96 ALDH1A1 (1.00) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL21144 0.96 ALDH1A1 (1.00) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL2773352 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL10881913 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL23248447 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL10883678 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL234787 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL10884509 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL10882319 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2250218-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION Pirelli Tyre S.P.A. (IT) 2010-11-17 — — EP claimed
WO-2009107151-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2009-09-03 — — WO claimed
US-20090199945-A1 Tire and Crosslinkable Elastomeric Composition POLITECNICO DI MILANO (50%) (IT) 2009-08-13 — — US claimed
EP-1533336-B1 Rubber mixtures EVONIK DEGUSSA GMBH (DE) 2009-01-14 — — EP claimed
EP-1991431-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.p.A. (IT) 2008-11-19 — — EP claimed
WO-2007098784-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2007-09-07 — — WO claimed
EP-2250218-B1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI (IT) 2017-04-05 — — EP disclosed
EP-2250218-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION Pirelli Tyre S.P.A. (IT) 2010-11-17 — — EP disclosed
EP-1991431-B1 TIRE MADE OF A CROSSLINKED ELASTOMERIC COMPOSITION PIRELLI (IT) 2010-07-21 — — EP disclosed
WO-2009107151-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2009-09-03 — — WO disclosed
US-20090199945-A1 Tire and Crosslinkable Elastomeric Composition POLITECNICO DI MILANO (50%) (IT) 2009-08-13 — — US disclosed
EP-1991431-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.p.A. (IT) 2008-11-19 — — EP disclosed
WO-2007098784-A1 TIRE AND CROSSLINKABLE ELASTOMERIC COMPOSITION PIRELLI TYRE S.P.A. (IT) 2007-09-07 — — WO disclosed
US-20050155687-A1 Tyre for vehicle wheels, tread band and elastomeric composition used therein PIRELLI PNEUMATICI S.P.A. (IT) 2005-07-21 — — US disclosed
US-20040192816-A1 Product in subdivided form for preparing crosslinkable elastomeric compositions PIRELLI PNEUMATICI S.P.A. (IT) 2004-09-30 — — US disclosed
EP-1456293-A1 TYRE FOR VEHICLE WHEELS, TREAD BAND AND ELASTOMERIC COMPOSITION USED THEREIN Pirelli Pneumatici S.p.A. (IT) 2004-09-15 — — EP disclosed
EP-1385905-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.p.A. (IT) 2004-02-04 — — EP disclosed
WO-2003054081-A1 TYRE FOR VEHICLE WHEELS, TREAD BAND AND ELASTOMERIC COMPOSITION USED THEREIN PIRELLI PNEUMATICI S.P.A. (IT) 2003-07-03 — — WO disclosed
WO-2002083783-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.P.A. (IT) 2002-10-24 — — WO disclosed