Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 1.00 |
| ▸ | TACR1 | P25103 | 10/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743921 | 1.00 | GHSR (1.00) | GHSRTACR1CCR3CYP3A4CYP3A5 | |
| SCHEMBL3640133 | 1.00 | GHSR (1.00) | GHSRTACR1CCR3CYP3A4CYP3A5 | |
| SCHEMBL3635981 | 1.00 | GHSR (1.00) | GHSRTACR1CCR3CYP3A4CYP3A5 | |
| Hydrochloric Acid SCHEMBL3635333 | 0.99 | GHSR (0.98) | GHSRTACR1CCR3CYP3A4CYP3A5 | |
| SCHEMBL3636638 | 0.90 | GHSR (0.81) | GHSRTACR1CCR3KCNH2CCR2 | |
| SCHEMBL3746594 | 0.87 | GHSR (0.78) | GHSRTACR1CCR3KCNH2 | |
| SCHEMBL3638783 | 0.86 | GHSR (0.76) | GHSRTACR1CCR3KCNH2 | |
| SCHEMBL3635762 | 0.86 | GHSR (0.76) | GHSRTACR1CCR3KCNH2 | |
| SCHEMBL3742797 | 0.83 | GHSR (0.71) | GHSRTACR1CCR3KCNH2 | |
| SCHEMBL3747878 | 0.83 | GHSR (0.71) | GHSRTACR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| WO-2008148854-A1 | GHRELIN MODULATORS | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008148854-A1 | GHRELIN MODULATORS | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | GHSR 2/4885TACR1 56/4885CCR3 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.