Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570579 | 0.82 | CYP2C19 (0.47) | CYP1A2LMNACYP2C9CYP2C19HIF1A | |
| SCHEMBL7899580 | 0.82 | CYP2C19 (0.47) | CYP1A2LMNACYP2C9CYP2C19HIF1A | |
| SCHEMBL584028 | 0.82 | CYP2C19 (0.47) | CYP1A2LMNACYP2C9CYP2C19HIF1A | |
| SCHEMBL6178344 | 0.80 | CYP1A2 (0.51) | KCNA5CYP1A2CYP3A4LMNACYP11B1 | |
| Ammonia Solution, Strong SCHEMBL3396016 | 0.80 | CYP2C19 (0.45) | CYP1A2LMNACYP2C9CYP2C19HIF1A | |
| SCHEMBL27989626 | 0.78 | KCNA5 (0.46) | KCNA5CYP1A2CYP3A4LMNACYP11B1 | |
| SCHEMBL5929544 | 0.78 | KCNA5 (0.46) | KCNA5CYP1A2CYP3A4LMNACYP11B1 | |
| SCHEMBL30435487 | 0.77 | CYP1A2 (0.56) | KCNA5CYP1A2CYP3A4LMNACYP11B1 | |
| SCHEMBL1827065 | 0.77 | CYP1A2 (0.56) | KCNA5CYP1A2CYP3A4LMNACYP11B1 | |
| SCHEMBL4220721 | 0.77 | KCNA5 (0.47) | KCNA5CYP1A2CYP3A4LMNACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | KCNA5 1552/4885CYP1A2 4013/4885CYP3A4 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.