SCHEMBL374298

SCHEMBL374298

O=C(O)CC(O)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30972500 1.00
SCHEMBL2687087 1.00
SCHEMBL1405707 1.00
Bicarbonate SCHEMBL17054410 0.97 SLC22A6 (0.63)
SCHEMBL30641549 0.87 SLC22A6 (0.57)
SCHEMBL17204173 0.87 SLC22A6 (0.57)
SCHEMBL2227091 0.87 SLC22A6 (0.57)
SCHEMBL1135965 0.87 SLC22A6 (0.57)
SCHEMBL8893904 0.87 SLC22A6 (0.57)
SCHEMBL3371887 0.87 SLC22A6 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 709 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143688-B Construction and application of recombinant escherichia coli 鲁南制药集团股份有限公司 2024-05-07 CN claimed
CN-117843473-A Preparation method of levocarnitine impurity 常州寅盛药业有限公司 2024-04-09 CN claimed
CN-117843509-A Preparation method of levocarnitine impurity 常州寅盛药业有限公司 2024-04-09 CN claimed
CN-117757826-A Recombinant expression plasmid of short-chain dehydrogenase, recombinant genetically engineered bacterium and application thereof 浙江工业大学 2024-03-26 CN claimed
CN-117757690-A Burkholderia cepacia (Burkholderia cepacia) WZ-5 and application thereof 浙江工业大学 2024-03-26 CN claimed
CN-113652408-B Carbonyl reductase mutant and application thereof in synthesis of (R) -4-chloro-3-hydroxybutyrate ethyl ester 华东理工大学 2024-02-20 CN claimed
CN-117402843-A Ketoreductase from schizosaccharomyces japonica yFS275 and application thereof 万华化学集团股份有限公司 2024-01-16 CN claimed
CN-117402839-A Ketoreductase and application thereof in preparation of (R) -4-chloro-3-hydroxybutyrate 万华化学集团股份有限公司 2024-01-16 CN claimed
CN-117384868-A Engineered ketoreductase and method for preparing chiral alcohol compounds 宁波酶赛生物工程有限公司 2024-01-12 CN claimed
CN-114380706-B Method and device for continuously preparing L-carnitine at low cost 浙江财和生物科技有限公司 2024-01-09 CN claimed
US-5700670-A TREATING MICROORGANISM CULTURE WITH ALKYL ESTER OF GAMMA-SUBSTITUTED ACETOACETIC ACID FOR STEREOSPECIFIC REDUCTION OF CARBONYL GROUP TO HYDROXYL GROUP YIELDS GAMMA-SUBSTITUTED 3-HYDROXYBUTYRIC ACID MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-23 US claimed
US-5614641-A USING A PHOSPHINO-CONTAINING RUTHENIUM COMPLEX AS CATALYST ELF AQUITAINE (FR) 1997-03-25 US claimed
EP-0648201-B1 ENANTIOSELECTIVE HYDROGENATION OF THE CARBONYL BOND USING RUTHENIUM COMPLEXES WITH BIPHOSPHINE LIGANDS ELF AQUITAINE (FR) 1997-01-22 EP claimed
EP-0737751-A2 Method for producing optically active ester of gamma-substituted-beta-hydroxybutyric acid Mitsubishi Chemical Corporation (JP) 1996-10-16 EP claimed
EP-0648201-A1 Enantioselective hydrogenation of the carbonyl bond using ruthenium complexes with biphosphine ligands. ELF AQUITAINE (FR) 1995-04-19 EP claimed
WO-1994001390-A1 ENANTIOSELECTIVE CARBONYL GROUP HYDROGENATION METHOD USING RUTHENIUM/DIPHOSPHINE LIGAND COMPLEXES ELF AQUITAINE (FR) 1994-01-20 WO claimed
EP-0288994-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS Chisso Corporation (JP) 1992-07-22 EP claimed
EP-0223328-B1 PROCESS FOR PRODUCING OXIRACETAM DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-01-29 EP claimed
US-4962031-A SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES CHISSO CORPORATION (JP) 1990-10-09 US claimed
EP-0288994-A2 Process for producing optically active compounds Chisso Corporation (JP) 1988-11-02 EP claimed