SCHEMBL3743340

SCHEMBL3743340

B.Nc1cc(N)cc(N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
CYP3A4 P08684 6/20 0.50
TSHR P16473 3/20 0.50
CASP1 P29466 2/20 0.50
RECQL P46063 1/20 0.50
TP53 P04637 2/20 0.47
MAPT P10636 2/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PTK2 Q05397 1/20 0.42
CYP19A1 P11511 1/20 0.40
THRB P10828 1/20 0.39
TDP1 Q9NUW8 2/20 0.33
BRD4 O60885 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63148 0.94
Ammonia Solution, Strong SCHEMBL28131976 0.89 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRCASP1RECQL
Water SCHEMBL27324157 0.89 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRCASP1RECQL
Hydrochloric Acid SCHEMBL2351290 0.89 CYP3A4 (0.50) ALDH1A1CYP3A4TSHRCASP1RECQL
Hydrochloric Acid SCHEMBL3077514 0.89 CYP3A4 (0.50) ALDH1A1CYP3A4TSHRCASP1RECQL
Methylamine SCHEMBL28176622 0.84 ALDH1A1 (0.57) ALDH1A1CYP3A4TSHRCASP1RECQL
SCHEMBL9402959 0.80 CYP3A4 (0.44) ALDH1A1CYP3A4TSHRCASP1RECQL
Methyl Alcohol SCHEMBL29286780 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRCASP1RECQL
SCHEMBL6086474 0.77
SCHEMBL178488 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7834212-B2 Lightweight, and has a highly developed pore structure,good gas absorbability; by dehydrogenating a compound having two or more amine-borane adduct NIPPON OIL CORPORATION (JP) 2010-11-16 US disclosed
US-20080095684-A1 Lightweight, and has a highly developed pore structure,good gas absorbability; by dehydrogenating a compound having two or more amine-borane adduct NIPPON OIL CORPORATION (JP) 2008-04-24 US disclosed