Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067 | 0.87 | APP (0.65) | APPCYP1A2MAPTALDH1A1RAB9A | |
| Water SCHEMBL1094033 | 0.86 | APP (0.63) | APPCYP1A2MAPTALDH1A1RAB9A | |
| SCHEMBL1096453 | 0.86 | APP (0.63) | APPCYP1A2MAPTALDH1A1RAB9A | |
| Phosphoric Acid SCHEMBL307362 | 0.81 | APP (0.61) | APPCYP1A2MAPTALDH1A1RAB9A | |
| Acetic Acid SCHEMBL233001 | 0.79 | APP (0.59) | APPCYP1A2MAPTALDH1A1RAB9A | |
| SCHEMBL532224 | 0.79 | APP (0.59) | APPCYP1A2MAPTALDH1A1RAB9A | |
| Pyrophosphoric Acid SCHEMBL12479170 | 0.76 | APP (0.56) | APPCYP1A2MAPTALDH1A1RAB9A | |
| Bromoacetic Acid SCHEMBL1896728 | 0.76 | APP (0.56) | APPCYP1A2MAPTALDH1A1RAB9A | |
| SCHEMBL6813575 | 0.76 | APP (0.56) | APPCYP1A2MAPTALDH1A1RAB9A | |
| Pivalate SCHEMBL6813805 | 0.76 | APP (0.56) | APPCYP1A2MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624382-B2 | Beta-lactam compounds and methods of use thereof | THE UNIVERSITY OF HONG KONG (HK) | 2026-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624382-B2 | Beta-lactam compounds and methods of use thereof | COASY, MB, SI | APP 1677/4885CYP1A2 269/4885MAPT 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.