SCHEMBL374360

SCHEMBL374360

O=CC(Cl)(Cl)Cl.O=CC(Cl)(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75613 1.00
SCHEMBL3293884 1.00
Ammonia Solution, Strong SCHEMBL8056746 0.95
Water SCHEMBL34328 0.95
SCHEMBL31326079 0.95
SCHEMBL23064423 0.95
Hydrochloric Acid SCHEMBL9658417 0.95
SCHEMBL9903913 0.95
Charcoal, Activated SCHEMBL12520682 0.95
Carbon Tetrachloride SCHEMBL11147171 0.95 ALDH1A1 (0.40) ALDH1A1LMNACYP2E1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019002344-A1 METHOD FOR PREPARATION OF ALPHA-METHYL-L-PROLINE LONZA GUANGZHOU NANSHA LTD. (CN) 2019-01-03 WO disclosed
US-20120022275-A1 PROCESS FOR THE PRODUCTION OF CARNITINE BY CYCLOADDITION LONZA LTD. (CH) 2012-01-26 US disclosed
EP-2409965-A1 A process for the production of carnitine by cycloaddition Lonza Ltd. (CH) 2012-01-25 EP disclosed
US-4699824-A THERMOSET AMINO OR PHENOLIC RESIN SUBSTRATE WITH PRESSURE SENSITIVE ADHESIVE PUFAHL JOSEPH (US) 1987-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022275-A1 PROCESS FOR THE PRODUCTION OF CARNITINE BY CYCLOADDITION CRAT, CPT2, CPT1B ALDH1A1 832/4885LMNA 371/4885CYP2E1 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.