Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637374 | 1.00 | KMT2A (0.43) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL13984537 | 0.82 | KMT2A (0.43) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL3739429 | 0.79 | MEN1 (0.43) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL3634477 | 0.79 | MEN1 (0.43) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL3637907 | 0.78 | KMT2A (0.44) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL3746272 | 0.78 | MEN1 (0.46) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL3637387 | 0.78 | MEN1 (0.46) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL3637861 | 0.77 | KMT2A (0.43) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL13044870 | 0.76 | CHRM2 (0.39) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL13044806 | 0.76 | KMT2A (0.42) | KMT2AMEN1ALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | KMT2A 3646/4885MEN1 3070/4885ALDH1A1 2645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.