Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136294 | 0.93 | CYP2B6 (0.42) | CYP2B6POLBKMT2AMEN1CYP2C9 | |
| SCHEMBL1528523 | 0.88 | CYP2B6 (0.36) | CYP2B6POLBKMT2AMEN1CYP2C9 | |
| SCHEMBL9650536 | 0.82 | CYP2B6 (0.46) | CYP2B6CYP11B1CYP11B2SMN1; SMN2KCNH2 | |
| SCHEMBL3707837 | 0.80 | CYP2B6 (0.63) | CYP2B6POLBKMT2AMEN1CYP2C9 | |
| SCHEMBL27753492 | 0.78 | CYP2B6 (0.54) | CYP2B6KMT2AMEN1CYP2C9CYP11B1 | |
| SCHEMBL2392136 | 0.78 | CYP2B6 (0.59) | CYP2B6KMT2AMEN1CYP2C9CYP11B1 | |
| SCHEMBL4400626 | 0.77 | CYP2B6 (0.42) | CYP2B6KMT2AMEN1CYP2C9NPC1 | |
| SCHEMBL19296941 | 0.76 | CYP2B6 (0.63) | CYP2B6KMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL2491599 | 0.76 | CYP2B6 (0.63) | CYP2B6KMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL441637 | 0.74 | CYP2B6 (0.41) | CYP2B6CYP11B1CYP11B2SMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484446-A | Clopidogrel metabolic active body disulfide derivative, preparation method and medical application thereof | 北京翼方生物科技有限责任公司 | 2020-08-04 | — | — | CN | claimed |
| CN-105481760-A | Preparation method of derivative tipidogrel active metabolite | TIANJIN INST PHARMACEUTICAL CO LTD | 2016-04-13 | — | — | CN | claimed |
| US-20250206884-A1 | ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL | TAICA CORPORATION (JP) | 2025-06-26 | — | — | US | disclosed |
| CN-118974144-A | Ultraviolet-curable polysiloxane composition and damping material | 株式会社泰已科 | 2024-11-15 | — | — | CN | disclosed |
| CN-116947743-A | Nitrosothiol compound and synthesis method and application thereof | 南京雷正医药科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2023189433-A1 | ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL | 株式会社タイカ | 2023-10-05 | — | — | WO | disclosed |
| CN-112851570-A | Preparation method and medical application of unsaturated cyclic amine cysteine disulfide derivative | 北京沃邦医药科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112812098-A | Preparation method and medical application of unsaturated cyclic amine pyridine disulfide derivative | 北京沃邦医药科技有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-111484446-A | Clopidogrel metabolic active body disulfide derivative, preparation method and medical application thereof | 北京翼方生物科技有限责任公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111362864-A | Unsaturated cyclic amine disulfide derivative, preparation method and medical application thereof | 北京翼方生物科技有限责任公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-105481760-A | Preparation method of derivative tipidogrel active metabolite | TIANJIN INST PHARMACEUTICAL CO LTD | 2016-04-13 | — | — | CN | disclosed |
| US-5466687-A | Anticholesterol agents | DR. KARL THOMAE GMBH (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0596326-B1 | Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production | THOMAE GMBH DR K (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0321191-B1 | Heterocyclic-substituted quinoline-carboxylic acids | PFIZER (US) | 1994-11-02 | — | — | EP | disclosed |
| CN-1090849-A | Arylidene-1-azacycloparaffin and aralkyl-1-azacycloparaffin, their salt contains medicament and the application and their preparation process of these compounds | THOMAE GMBH DR K (DE) | 1994-08-17 | — | — | CN | disclosed |
| EP-0596326-A1 | Arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes, their salts, medicaments containing the same, use thereof and precesses for their production | Dr. Karl Thomae GmbH (DE) | 1994-05-11 | — | — | EP | disclosed |
| US-5214051-A | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed | PFIZER INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5037834-A | Heterocycylic-substituted quinoline-carboxylic acids | PFIZER INC. (US) | 1991-08-06 | — | — | US | disclosed |
| WO-1989005643-A1 | HETEROCYCLIC-SUBSTITUTED QUINOLINE-CARBOXYLIC ACIDS | PFIZER INC. (US) | 1989-06-29 | — | — | WO | disclosed |
| EP-0321191-A2 | Heterocyclic-substituted quinoline-carboxylic acids | PFIZER INC. (US) | 1989-06-21 | — | — | EP | disclosed |