Ethylene Glycol

Ethylene Glycol

SCHEMBL3744577

COC(C(=O)O)C(O)C(=O)O.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
TSHR P16473 2/20 0.39
CYP2C9 P11712 1/20 0.37
PDE4A P27815 1/20 0.37
PGD P52209 2/20 0.35
OR51E2 Q9H255 1/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
TP53 P04637 1/20 0.32
TGFBR1 P36897 1/20 0.31
GBA1 P04062 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL3733977 0.91 SLC1A3 (0.43) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL722389 0.91 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL7291825 0.91 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL7290471 0.91 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL27742181 0.88 SLC1A3 (0.52) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
Di(Hydroxyethyl)Ether SCHEMBL3746401 0.88 SLC1A3 (0.41) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
Propylene Glycol SCHEMBL3726880 0.87 SLC1A3 (0.43) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
Tetraethylene Glycol SCHEMBL3733135 0.86 MEN1 (0.41) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
Triethylene Glycol SCHEMBL3731837 0.86 MEN1 (0.41) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL3731111 0.83 GAA (0.38) SLC1A3SLC1A2SLC1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed