SCHEMBL3745007

SCHEMBL3745007

CC(CCCOCC1CO1)C(C)(C)O[SiH3]

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15610114 0.84 SMN1; SMN2 (0.51) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL19411059 0.78 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28633009 0.78 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28305886 0.78 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2431711 0.78 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL29156594 0.77 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10585663 0.77 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1402713 0.76 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614904 0.75 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL153464 0.74 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332188-A Process method for circularly producing trichlorosilane 湖北江瀚新材料股份有限公司 2023-06-27 CN disclosed
US-20160185916-A1 METHODS OF MAKING SACCHARIDE SILOXANE COPOLYMERS DOW CORNING (US) 2016-06-30 US disclosed
US-9315631-B2 Methods of making saccharide siloxane copolymers DOW CORNING CORPORATION (US) 2016-04-19 US disclosed
US-20140357884-A1 Methods of Making Saccharide Siloxane Copolymers DOW CORNING CORPORATION (US) 2014-12-04 US disclosed
EP-2804890-A1 METHODS OF MAKING SACCHARIDE SILOXANE COPOLYMERS Dow Corning Corporation (US) 2014-11-26 EP disclosed
US-8835564-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-16 US disclosed
US-20140088256-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
WO-2013109523-A1 METHODS OF MAKING SACCHARIDE SILOXANE COPOLYMERS DOW CORNING CORPORATION (US) 2013-07-25 WO disclosed
US-7838616-B2 Perfluoropolyether rubber composition and ion-conducting polymer electrolyte membrane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-23 US disclosed
US-20080107950-A1 PERFLUOROPOLYETHER RUBBER COMPOSITION AND ION-CONDUCTING POLYMER ELECTROLYTE MEMBRANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-05-08 US disclosed
EP-0548973-B1 Inhibited epoxysilanes OSI SPECIALTIES INC (US) 1997-09-24 EP disclosed
EP-0548973-A2 Inhibited epoxysilanes OSi Specialties, Inc. (US) 1993-06-30 EP disclosed
US-5155233-A Stabilized with diphenylamine UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-10-13 US disclosed
US-4931328-A Capillary tube with reduced protein interactions and controllable electroosmotic flow HEWLETT-PACKARD COMPANY (US) 1990-06-05 US disclosed
EP-0354984-A2 Capillary tube with reduced protein interactions and controllable electroosmotic flow Hewlett-Packard Company (US) 1990-02-21 EP disclosed