Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 5/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 7/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746158 | 1.00 | APEX1 (0.43) | APEX1IMPDH2ALOX5FASNPTGES | |
| SCHEMBL3751380 | 0.91 | APEX1 (0.53) | APEX1IMPDH2ALOX5PTGESPPARG | |
| SCHEMBL3751383 | 0.91 | APEX1 (0.53) | APEX1IMPDH2ALOX5PTGESPPARG | |
| SCHEMBL3744526 | 0.88 | APEX1 (0.55) | APEX1ALOX5PPARG | |
| SCHEMBL3744524 | 0.88 | APEX1 (0.55) | APEX1ALOX5PPARG | |
| SCHEMBL3750607 | 0.87 | APEX1 (0.35) | APEX1IMPDH2 | |
| SCHEMBL3750604 | 0.87 | APEX1 (0.35) | APEX1IMPDH2 | |
| SCHEMBL3750465 | 0.86 | APEX1 (0.52) | APEX1IMPDH2 | |
| SCHEMBL3750461 | 0.86 | APEX1 (0.52) | APEX1IMPDH2 | |
| SCHEMBL13080194 | 0.85 | MEN1 (0.36) | APEX1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9089605-B2 | Quinone derivatives, pharmaceutical compositions, and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |
| US-20100297113-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297113-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | APEX1, NQO1, REV1 | APEX1 1/4885IMPDH2 568/4885ALOX5 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.