SCHEMBL3746232

SCHEMBL3746232

O=S(=O)(O)c1cc(S(=O)(=O)O)c(Br)c(S(=O)(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
ING2 Q9H160 1/20 0.41
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 4/20 0.38
CASP6 P55212 3/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
LMNA P02545 1/20 0.37
NT5E P21589 3/20 0.36
TDP1 Q9NUW8 2/20 0.35
SUMO2 P61956 1/20 0.34
SUMO1 P63165 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP2 Q9HC62 1/20 0.34
NSD2 O96028 3/20 0.33
TIMP3 P35625 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4337628 0.82 ACP1 (0.35) LCKFYNTSHRALDH1A1HSD17B10
SCHEMBL10133590 0.78 CA1 (0.41) TSHRCASP6NSD2
SCHEMBL5420687 0.77 LCK (0.44) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL3495112 0.77 ING2 (0.54) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL3136473 0.77 LCK (0.44) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL5126356 0.77 LCK (0.44) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL3899723 0.77 ALDH1A1 (0.48) LCKFYNING2TSHRSMN1; SMN2
SCHEMBL9950644 0.76 CA1 (0.39) TSHRCASP6NSD2
SCHEMBL11778575 0.76 CA1 (0.52) LCKFYNING2TSHRALDH1A1
SCHEMBL3816121 0.75 ALDH1A1 (0.47) LCKFYNING2TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838594-B2 Aromatic sulfonimide ionene polymers useful in electrochemical cells, fuel cells, electrolyte membranes; electroconductive polymers; ionic liquids with bisperfluoroalkylsulfonimide anion E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-23 US disclosed
US-20090171067-A1 BRIDGED ARYLENE FLUORINATED SULFONIMIDE COMPOSITIONS AND POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-07-02 US disclosed
US-7456321-B2 Process for producing high-purity 4,4′-dihydroxydiphenyl sulfone KONISHI CHEMICAL IND. CO., LTD. (JP) 2008-11-25 US disclosed
CN-1314664-C Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone KONISHI CHEM IND (JP) 2007-05-09 CN disclosed
US-20050272956-A1 Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone KONISHI CHEMICAL IND. CO., LTD. (JP) 2005-12-08 US disclosed
CN-1684943-A Process for producing high-purity 4,4'-dihydroxydiphenyl sulfone KONISHI CHEM IND (JP) 2005-10-19 CN disclosed
EP-0443046-B1 PROCESS FOR PREPARING 4,4'-DIHYDROXYDIPHENYL SULFONE KONISHI CHEM IND (JP) 1994-04-13 EP disclosed
US-5189223-A PROCESS FOR PREPARATION OF 4,4'-DIHYDROXYDIPHENYLSULFONE KONISHI CHEMICAL IND. CO., LTD. (JP) 1993-02-23 US disclosed
EP-0443046-A1 PROCESS FOR PREPARING 4,4'-DIHYDROXYDIPHENYL SULFONE KONISHI CHEMICAL IND. CO., LTD. (JP) 1991-08-28 EP disclosed