SCHEMBL3746335

SCHEMBL3746335

CCC1OC1CC=CCC1OC1CCCCCCCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
F7 P08709 4/20 0.41
F3 P13726 4/20 0.41
PPARG P37231 4/20 0.41
PPARD Q03181 4/20 0.41
PPARA Q07869 4/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP19A1 P11511 3/20 0.41
BLM P54132 3/20 0.41
HSD17B10 Q99714 3/20 0.41
LMNA P02545 2/20 0.41
ALOX15 P16050 2/20 0.41
PTGS1 P23219 2/20 0.41
RECQL P46063 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
OXER1 Q8TDS5 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17547604 1.00 MAPT (0.54) MAPTF7F3PPARGPPARD
SCHEMBL6244558 0.94 MAPT (0.54) MAPTF7F3PPARGPPARD
SCHEMBL2482201 0.90 GPR84 (0.48) PPARGPPARDPPARAALDH1A1HSD17B10
SCHEMBL11538646 0.90 GPR84 (0.48) PPARGPPARDPPARAALDH1A1HSD17B10
SCHEMBL3742738 0.90 MAPT (0.60) MAPTF7F3PPARGPPARD
SCHEMBL3742728 0.90 MAPT (0.50) MAPTF7F3PPARGPPARD
SCHEMBL5374521 0.90 MAPT (0.60) MAPTF7F3PPARGPPARD
SCHEMBL3742740 0.90 MAPT (0.60) MAPTF7F3PPARGPPARD
SCHEMBL17547609 0.90 MAPT (0.50) MAPTF7F3PPARGPPARD
SCHEMBL3702490 0.88 MAPT (0.69) MAPTF7F3PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7834248-B2 comprising 12,13-epoxy-9-octadecenoic acid; generation of preferential coatings, resins, glues, plastics, surfactants and lubricants from renewable plant sources COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-11-16 US disclosed
US-7589253-B2 Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2009-09-15 US disclosed
CN-100482797-C Plant fatty acid epoxygenase genes and uses therefor COMMW SCIENT IND RES ORG (AU) 2009-04-29 CN disclosed
US-20070209092-A1 Plant seed comprising vernolic acid COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, BASF PLANT SCIENCE, GMBH 2007-09-06 US disclosed
EP-0975765-B1 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMW SCIENT IND RES ORG (AU) 2006-10-11 EP disclosed
US-20020166144-A1 Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism BASF PLANT SCIENCE GMBH (DE) 2002-11-07 US disclosed
EP-0975765-A4 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMW SCIENT IND RES ORG (AU) 2002-09-25 EP disclosed
US-6329518-B1 NUCLEIC ACID FROM CREPIS PLANT CODING FOR ENZYME THAT CATALYZES EPOXYGENATION OF CARBON DOUBLE BOND AT DELTA-12 POSITION OF FATTY ACID; EFFICIENT PRODUCTION OF COATINGS, GLUES, PLASTICS, SURFACTANTS AND LUBRICANTS BASF PLANT SCIENCE GMBH (DE) 2001-12-11 US disclosed
CN-1257541-A Plant fatty acid epoxidase and its use COMMW SCIENT IND RES ORG (AU) 2000-06-21 CN disclosed
EP-0975765-A1 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-02-02 EP disclosed
WO-1998046762-A1 PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-10-22 WO disclosed