SCHEMBL3746459

SCHEMBL3746459

C=C(C)C(=O)OC(CC)[Si](C)(C)Br

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477683 0.87 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL1677860 0.85 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL7864106 0.83 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL3744246 0.81 TSHR (0.37) TSHRALDH1A1THRB
Lithium Ion SCHEMBL2144025 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL3741210 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL8074770 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL933010 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL7179413 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL1719176 0.81 TSHR (0.37) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140050917-A1 LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES NANOFILM LTD. (US) 2014-02-20 US claimed
US-20140050917-A1 LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES NANOFILM LTD. (US) 2014-02-20 US disclosed
US-7834120-B2 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
EP-1645560-B1 Monofunctional monomer having cage oligosiloxane structure and method of making SHINETSU CHEMICAL CO (JP) 2008-05-28 EP disclosed
EP-1645560-A1 Monofunctional monomer having cage oligosiloxane structure and method of making Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20060074213-A1 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-04-06 US disclosed
US-6307081-B1 MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. DOW CORNING SILICONE COMPANY, LTD. (JP) 2001-10-23 US disclosed