SCHEMBL933010

SCHEMBL933010

C=C(C)C(=O)OC(CC)[Si](C)(C)Cl

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1719176 0.89 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL524563 0.87 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL17541578 0.86 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL7866733 0.85 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL1677860 0.85 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL9154189 0.84 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL7864106 0.83 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL931884 0.82 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL7858554 0.82 TSHR (0.44) TSHR
SCHEMBL3744246 0.81 TSHR (0.37) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221944-A Preparation method of acrylic ester modified silicone oil for silicone hydrogel type contact lens 苏州矽合高新材料科技有限公司 2024-06-21 CN claimed
CN-118108947-A Preparation of methacrylate double-end-capped dimethyl silicone oil for contact lens 苏州矽合高新材料科技有限公司 2024-05-31 CN claimed
EP-4363498-A1 HIGH WATER CONTENT BIOMEDICAL DEVICES Bausch + Lomb Ireland Limited (IE) 2024-05-08 EP claimed
CN-113683934-B High-transparency washable acrylate anti-corrosion coating and preparation method thereof 浙江理工大学 2023-10-03 CN claimed
CN-116041789-A Organic silicon resin modified silicon dioxide nano particle and preparation method and application thereof 华南理工大学 2023-05-02 CN claimed
WO-2023274748-A1 HIGH WATER CONTENT BIOMEDICAL DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2023-01-05 WO claimed
CN-114854021-A Preparation method of unilateral reaction type functional group end-capped silicone oil 希立科高新材料科技(苏州)有限公司 2022-08-05 CN claimed
CN-110265608-B Nano coating diaphragm for high-voltage-resistant lithium ion battery and preparation method thereof 新乡市中科科技有限公司 2021-10-01 CN claimed
CN-108179235-B Tanning agent prepared from modified rice dialdehyde starch 温州大学 2020-09-29 CN claimed
US-20140050917-A1 LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES NANOFILM LTD. (US) 2014-02-20 US claimed
EP-0268243-B1 Packing material and process for its production TOSOH CORP (JP) 1997-08-13 EP claimed
EP-0775708-A2 Method for the preparation of high-purity methacryloxypropyldimethylchlorosilane Dow Corning Toray Silicone Company Ltd. (JP) 1997-05-28 EP claimed
US-5567789-A Method for the preparation of organopolysiloxanes DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-10-22 US claimed
US-5567790-A Method for the preparation of diphenylsiloxane-dimethylsiloxane copolymers DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-10-22 US claimed
US-5493039-A Method for the preparation of methacryloxypropyldimethylchlorosilane DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-02-20 US claimed
EP-0693521-A1 Method for the preparation of diphenylsiloxane-dimethylsiloxane copolymers Dow Corning Toray Silicone Company, Limited (JP) 1996-01-24 EP claimed
EP-0693492-A1 Method for preparation of methacryloxypropyldimethylchlorosilane Dow Corning Toray Silicone Company, Limited (JP) 1996-01-24 EP claimed
EP-0693520-A1 Method for the preparation of organopolysiloxanes Dow Corning Toray Silicone Company, Limited (JP) 1996-01-24 EP claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
EP-0268243-A2 Packing material and process for its production Tosoh Corporation (JP) 1988-05-25 EP claimed