Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637676 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL3637111 | 0.84 | TSHR (0.38) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL3638555 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1NPC1TDP1KDM2B | |
| SCHEMBL3746272 | 0.73 | MEN1 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL3637387 | 0.73 | MEN1 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL13044879 | 0.72 | TSHR (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL4910306 | 0.72 | CHRM2 (0.84) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL3637374 | 0.70 | KMT2A (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL3634477 | 0.70 | MEN1 (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL3739429 | 0.70 | MEN1 (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | CHRM2 1777/4885CHRM1 1896/4885CHRM4 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.