Dexanabinol

Dexanabinol

SCHEMBL3746646

CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(CO)CC21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 12/20 1.00
▸ CNR1 P21554 12/20 1.00
▸ GLRA1 P23415 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31545961 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL1517462 1.00 CNR2 (1.00) CNR2CNR1GLRA1
SCHEMBL17414497 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL1649687 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL1517460 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL5464644 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL5449597 1.00 CNR2 (1.00) CNR2CNR1GLRA1
SCHEMBL17414495 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL6954142 1.00 CNR2 (1.00) CNR2CNR1GLRA1
Dexanabinol SCHEMBL31545009 1.00 CNR2 (1.00) CNR2CNR1GLRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10450251-B2 Process for the preparation of 3-substituted cannabinoid compounds E-THERAPEUTICS PLC (GB) 2019-10-22 — — US claimed
US-20180354876-A1 PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CANNABINOID COMPOUNDS E-THERAPEUTICS PLC (GB) 2018-12-13 — — US claimed
US-7763607-B2 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2010-07-27 — — US claimed
EP-2026798-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS Solvay Pharmaceuticals GmbH (DE) 2009-02-25 — — EP claimed
WO-2007125048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 — — WO claimed
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US claimed
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US claimed
US-10450251-B2 Process for the preparation of 3-substituted cannabinoid compounds E-THERAPEUTICS PLC (GB) 2019-10-22 — — US disclosed
US-20180354876-A1 PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CANNABINOID COMPOUNDS E-THERAPEUTICS PLC (GB) 2018-12-13 — — US disclosed
EP-2841067-A2 A DRUG SCREENING PLATFORM FOR RETT SYNDROME The Regents of The University of California (US) 2015-03-04 — — EP disclosed
WO-2013163455-A2 A DRUG SCREENING PLATFORM FOR RETT SYNDROME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-10-31 — — WO disclosed
US-7763607-B2 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2010-07-27 — — US disclosed
EP-2026798-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS Solvay Pharmaceuticals GmbH (DE) 2009-02-25 — — EP disclosed
EP-2012775-A1 USE OF CBX CANNABINOID RECEPTOR MODULATORS AS POTASSIUM CHANNEL MODULATORS Solvay Pharmaceuticals GmbH (DE) 2009-01-14 — — EP disclosed
WO-2007125049-A1 USE OF CBX CANNABINOID RECEPTOR MODULATORS AS POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 — — WO disclosed
WO-2007125048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 — — WO disclosed
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators CNR2, CNR1, KCNN1 CNR2 1/4885CNR1 2/4885GLRA1 208/4885
US-20180354876-A1 PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CANNABINOID COMPOUNDS CNR1, CNR2, OPRK1 CNR2 2/4885CNR1 1/4885GLRA1 140/4885
US-10450251-B2 Process for the preparation of 3-substituted cannabinoid compounds CNR1, CNR2, CBR1 CNR2 2/4885CNR1 1/4885GLRA1 155/4885
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators CNR1, CNR2, KCNJ11 CNR2 2/4885CNR1 1/4885GLRA1 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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