SCHEMBL37469

SCHEMBL37469

O=C(O)c1ccncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29587616 1.00
Hydrochloric Acid SCHEMBL1224737 0.98 P2RX7 (0.57)
SCHEMBL31022254 0.98 P2RX7 (0.57)
SCHEMBL29062401 0.98 P2RX7 (0.57)
Bromide SCHEMBL10349040 0.98 P2RX7 (0.57)
SCHEMBL27705986 0.98 P2RX7 (0.57)
Hydrochloric Acid SCHEMBL28466502 0.98 P2RX7 (0.57)
SCHEMBL27474788 0.98 P2RX7 (0.57)
Acetic Acid SCHEMBL11881380 0.94 P2RX7 (0.53)
Urea SCHEMBL28223550 0.94 P2RX7 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2600 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775207-A Morpholine-containing amide compound and preparation method and application thereof 山东农业大学 2025-04-08 CN claimed
CN-118541353-A Bis (hetero) aryl thioether (thio) amides as fungicidal compounds 拜耳公司 2024-08-23 CN claimed
CN-118459506-A Iridium complex capable of preparing efficient device by using 4-pyrimidine formic acid as auxiliary ligand in solution 云南师范大学 2024-08-09 CN claimed
CN-118344873-A Silicon nitride etching solution for inhibiting tip oxide regeneration, preparation method and application 浙江奥首材料科技有限公司 2024-07-16 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-114304824-B Durable wear-resistant souvenir badge and preparation method thereof 北京华夏理想证章有限公司 2023-11-17 CN claimed
CN-116621783-A Pyrimidine hydrazide organic gel factor and preparation and application thereof 上海应用技术大学 2023-08-22 CN claimed
CN-114702506-B 11-carbonyl-20-ethoxy source oridonin and 14-OH esterified serial derivatives and application thereof 郑州大学 2023-08-22 CN claimed
EP-3379933-B1 FUNGICIDAL COMPOSITIONS CONTAINING DERIVATIVES OF 2,4-DIOXO-1,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE GILEAD APOLLO LLC (US) 2023-02-15 EP claimed
CN-112279888-B Polypeptide inhibitor of APC/Asef interaction and application thereof 上海交通大学医学院 2022-09-13 CN claimed
CN-1277612-A Nitrogen-containing heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2000-12-20 CN claimed
EP-0979034-A1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-02-16 EP claimed
CN-1206010-A 5H-thiazole [3,2-a] pyrimidine derivatives HOFFMANN LA ROCHE (CH) 1999-01-27 CN claimed
WO-1998048628-A1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 1998-11-05 WO claimed
EP-0169144-B1 PROCESS FOR THE PREPARATION OF 7-AMINO AND 7-SUBSTITUTED AMINO-DESACETOXYCEPHALOSPORINS FROM THE CORRESPONDING 6-SUBSTITUTED AMINO PENICILLIN SULPHOXIDES GEMA S.A. (ES) 1990-06-06 EP claimed
US-4767851-A Process for the preparation of 7-amino and 7-substituted amino-desacetoxycephalosporins GEMA, S.A. (ES) 1988-08-30 US claimed
CN-85107614-A The manufacture method of 4-alkoxyl group-pyrido (2,3-d) pyrimidine-derivative 1986-07-16 CN claimed
EP-0169144-A2 Process for the preparation of 7-amino and 7-substituted amino-desacetoxycephalosporins from the corresponding 6-substituted amino penicillin sulphoxides GEMA S.A. (ES) 1986-01-22 EP claimed
EP-0014390-B1 2-AMINO-8-CYCLOPROPYL-5-OXO-5,8-DIHYDRO-PYRIDO (2,3-D) PYRIMIDINE-6-CARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION BAYER AG (DE) 1982-02-03 EP claimed
EP-0014390-A1 2-Amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyrido (2,3-d) pyrimidine-6-carboxylic acids, pharmaceutical compositions containing them and processes for their preparation BAYER AG (DE) 1980-08-20 EP claimed