Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746337 | 1.00 | MAPT (0.60) | MAPTALOX5HMGCRPPARGPPARD | |
| SCHEMBL3738107 | 0.93 | MAPT (0.71) | MAPTPPARGPPARDPPARATERT | |
| SCHEMBL3741924 | 0.93 | MAPT (0.71) | MAPTALOX5PPARGPPARDPPARA | |
| SCHEMBL3735864 | 0.91 | MAPT (0.72) | MAPTALOX5HMGCRPPARGPPARD | |
| SCHEMBL3737730 | 0.90 | MAPT (0.79) | MAPTALOX5PPARGPPARDPPARA | |
| SCHEMBL3752243 | 0.90 | MAPT (0.79) | MAPTALOX5PPARGPPARDPPARA | |
| SCHEMBL3746603 | 0.89 | MAPT (0.77) | MAPTALOX5PPARGPPARDPPARA | |
| SCHEMBL3742728 | 0.89 | MAPT (0.50) | MAPTPPARGPPARDPPARATERT | |
| SCHEMBL3750682 | 0.89 | MAPT (0.77) | MAPTPPARGPPARDPPARATERT | |
| SCHEMBL17547609 | 0.89 | MAPT (0.50) | MAPTPPARGPPARDPPARATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834248-B2 | comprising 12,13-epoxy-9-octadecenoic acid; generation of preferential coatings, resins, glues, plastics, surfactants and lubricants from renewable plant sources | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-11-16 | — | — | US | disclosed |
| US-7589253-B2 | Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2009-09-15 | — | — | US | disclosed |
| US-20070209092-A1 | Plant seed comprising vernolic acid | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, BASF PLANT SCIENCE, GMBH | 2007-09-06 | — | — | US | disclosed |
| EP-0975765-B1 | PLANT FATTY ACID EPOXYGENASE GENES AND USES THEREFOR | COMMW SCIENT IND RES ORG (AU) | 2006-10-11 | — | — | EP | disclosed |
| US-20020166144-A1 | Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism | BASF PLANT SCIENCE GMBH (DE) | 2002-11-07 | — | — | US | disclosed |
| US-6329518-B1 | NUCLEIC ACID FROM CREPIS PLANT CODING FOR ENZYME THAT CATALYZES EPOXYGENATION OF CARBON DOUBLE BOND AT DELTA-12 POSITION OF FATTY ACID; EFFICIENT PRODUCTION OF COATINGS, GLUES, PLASTICS, SURFACTANTS AND LUBRICANTS | BASF PLANT SCIENCE GMBH (DE) | 2001-12-11 | — | — | US | disclosed |