Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556171 | 0.79 | KCNN4 (0.52) | KCNN4TAAR1SMN1; SMN2CYP2D6DRD2 | |
| SCHEMBL9740041 | 0.79 | KCNN4 (0.52) | KCNN4TAAR1SMN1; SMN2CYP2D6DRD2 | |
| SCHEMBL10408983 | 0.79 | KCNN4 (0.52) | KCNN4TAAR1SMN1; SMN2CYP2D6DRD2 | |
| SCHEMBL6325226 | 0.79 | KCNN4 (0.52) | KCNN4SMN1; SMN2CYP2D6DRD2DRD4 | |
| SCHEMBL15577796 | 0.76 | KCNN4 (0.43) | KCNN4CARM1PRMT6PRMT8TAAR1 | |
| SCHEMBL3320771 | 0.76 | KCNN4 (0.48) | KCNN4CARM1PRMT6PRMT8TAAR1 | |
| SCHEMBL8300792 | 0.76 | KCNN4 (0.48) | KCNN4SMN1; SMN2CYP2D6DRD2DRD4 | |
| SCHEMBL19660254 | 0.75 | KCNN4 (0.42) | KCNN4CARM1PRMT6PRMT8TAAR1 | |
| SCHEMBL7695254 | 0.75 | KCNN4 (0.42) | KCNN4CARM1PRMT6PRMT8TAAR1 | |
| SCHEMBL11032848 | 0.73 | KCNN4 (0.41) | KCNN4CARM1PRMT6PRMT8TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279995-A1 | Novel Ansamycin Derivatives | GUIBLIN ALEXANDER R | 2010-11-04 | — | — | US | disclosed |
| CN-101253154-A | Novel ansamycin derivatives | BIOTICA TECH LTD (GB) | 2008-08-27 | — | — | CN | disclosed |
| EP-1937644-A1 | NOVEL ANSAMYCIN DERIVATIVES | Biotica Technology Limited (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007026027-A1 | NOVEL ANSAMYCIN DERIVATIVES | BIOTICA TECHNOLOGY LTD. (GB) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279995-A1 | Novel Ansamycin Derivatives | BCL6, BCL3, BCL6B | KCNN4 3996/4885CARM1 3331/4885PRMT6 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.