Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 4/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753285 | 0.87 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1KDM4ELMNA | |
| SCHEMBL25148603 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL831503 | 0.84 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL13053995 | 0.82 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4ELMNAHPGD | |
| SCHEMBL2090729 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMOKEAP1NFE2L2MAPK1 | |
| SCHEMBL839680 | 0.77 | KDM4E (0.47) | ALDH1A1L3MBTL1KMOKDM4ELMNA | |
| SCHEMBL830844 | 0.77 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KMOKDM4ELMNA | |
| SCHEMBL3754265 | 0.76 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL830836 | 0.76 | KDM4E (0.46) | ALDH1A1L3MBTL1KMOKDM4ELMNA | |
| SCHEMBL830938 | 0.74 | KDM4E (0.37) | ALDH1A1L3MBTL1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298221-A1 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298221-A1 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | NAPRT, PNPO, FABP3 | ALDH1A1 1855/4885L3MBTL1 2518/4885KMO 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.