⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169059 | 0.68 | KDM4E (0.34) | — | |
| SCHEMBL1032107 | 0.67 | KMT2A (0.37) | — | |
| SCHEMBL4843148 | 0.65 | — | — | |
| SCHEMBL28271180 | 0.64 | ENPP3 (0.31) | — | |
| SCHEMBL17185665 | 0.64 | — | — | |
| SCHEMBL4506799 | 0.63 | — | — | |
| SCHEMBL4728163 | 0.61 | — | — | |
| SCHEMBL69570 | 0.61 | — | — | |
| SCHEMBL2340955 | 0.60 | — | — | |
| SCHEMBL5218684 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781512-B1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | UNIV SHANGHAI JIAOTONG (CN) | 2017-06-28 | — | — | EP | claimed |
| EP-2167487-A1 | PYRROLE DERIVATIVES AS P2Y12 ANTAGONISTS | Sanofi-Aventis (FR) | 2010-03-31 | — | — | EP | claimed |
| WO-2008155022-A1 | PYRROLE DERIVATIVES AS P2Y12 ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-12-24 | — | — | WO | claimed |
| CN-117120090-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-11-24 | — | — | CN | disclosed |
| EP-3043774-A2 | LIQUID PROTEIN FORMULATIONS CONTAINING IONIC LIQUIDS | Arsia Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015038811-A2 | LIQUID PROTEIN FORMULATIONS CONTAINING IONIC LIQUIDS | Arsia Therapeutics, Inc. (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | disclosed |
| EP-1633746-A1 | NEW INDOLE DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004101554-A1 | NEW INDOLE DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |