Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL332954 | 0.83 | — | — | |
| SCHEMBL5703612 | 0.62 | — | — | |
| SCHEMBL27716047 | 0.62 | — | — | |
| SCHEMBL28323943 | 0.62 | — | — | |
| Butadiene SCHEMBL9579687 | 0.62 | TDP1 (0.75) | TDP1 | |
| Propene SCHEMBL28161236 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL28079648 | 0.61 | — | — | |
| SCHEMBL2128293 | 0.61 | TDP1 (1.00) | TDP1 | |
| SCHEMBL14870 | 0.61 | — | — | |
| SCHEMBL5708652 | 0.61 | TDP1 (1.00) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254544-B1 | OIL-IN-WATER EMULSION COMPRISING AN AMPHIPHILIC POLYMER | OREAL (FR) | 2012-01-25 | — | — | EP | claimed |
| EP-1281395-B1 | Composition for cosmetic or dermatological use containing a triblock copolymer | OREAL (FR) | 2007-07-18 | — | — | EP | claimed |
| EP-1468669-B1 | An aqueous, sunscreen composition comprising at least a di- or tribloc copolymer and 4,4-diarylbutadien, and use thereof | OREAL (FR) | 2007-03-28 | — | — | EP | claimed |
| EP-1279398-B1 | Composition for topical use containing a diblock-polymer | OREAL (FR) | 2006-12-27 | — | — | EP | claimed |