Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931159 | 0.87 | MAPT (0.50) | KDM4EMAPTL3MBTL1GAANPC1 | |
| SCHEMBL25082184 | 0.85 | CNR2 (0.55) | KDM4EMAPTL3MBTL1GAANPC1 | |
| SCHEMBL2420211 | 0.77 | HTR3A (0.67) | KDM4EMAPTL3MBTL1GAANPC1 | |
| SCHEMBL29460463 | 0.77 | HTR3A (0.67) | KDM4EMAPTL3MBTL1GAANPC1 | |
| SCHEMBL2280216 | 0.76 | AKR1C3 (0.73) | KDM4EMAPTL3MBTL1GAANPC1 | |
| SCHEMBL11181819 | 0.76 | CYP1A2 (0.50) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28582795 | 0.74 | CYP1A2 (0.67) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL713218 | 0.74 | CYP1A2 (0.66) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31325779 | 0.74 | CYP1A2 (0.66) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28810100 | 0.74 | MAPT (0.51) | KDM4EMAPTL3MBTL1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-A | Chemical entities, composition and method | 润新生物公司 | 2019-06-07 | — | — | CN | disclosed |
| US-20100278837-A1 | Compositions And Methods For Reducing Cancer And Inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-11-04 | — | — | US | disclosed |